Viktil K K, Enstad M, Kutschera J, Smedstad L M, Schjøtt J
Haukeland Hospital Pharmacy, Bergen, Norway.
Pharm World Sci. 2001 Aug;23(4):153-8. doi: 10.1023/a:1011909827909.
This study describes polypharmacy among patients admitted to hospital with rheumatic diseases.
The study was performed in departments of rheumatology at nine Norwegian hospitals during five weeks in 1998. Pharmacists recorded all drugs on admittance among patients 18 years or older with rheumatic diseases.
Sixty percent of 313 patients had polypharmacy defined as the concurrent use of five or more drugs, and this was most frequent among the older patients. However, they used fewer antirheumatic drugs compared to the younger patients. With regard to the three most common drug groups, older patients used more corticosteroids, and less nonsteroidal antiinflammatory drugs (NSAIDs) and disease modifying antirheumatic drugs (DMARDs), compared to the younger. Eighty-four percent of patients on methotrexate used folic acid, but only 52% of the patients who used corticosteroids used calcium supplements.
Polypharmacy among patients with rheumatic diseases is common, and the present description could be useful for drug-related interventions.
本研究描述了因风湿性疾病住院患者的多重用药情况。
1998年，在挪威九家医院的风湿科进行了为期五周的研究。药剂师记录了18岁及以上患风湿性疾病住院患者入院时使用的所有药物。
313名患者中有60%存在多重用药情况，即同时使用五种或更多药物，且在老年患者中最为常见。然而，与年轻患者相比，他们使用的抗风湿药物较少。在三种最常用的药物类别方面，老年患者比年轻患者使用更多的皮质类固醇，而使用较少的非甾体抗炎药（NSAIDs）和改善病情抗风湿药（DMARDs）。使用甲氨蝶呤的患者中有84%使用叶酸，但使用皮质类固醇的患者中只有52%使用钙补充剂。
风湿性疾病患者多重用药情况常见，本描述可能有助于药物相关干预。
Zotero 插件