Wensing M, Vingerhoets E, Grol R
Centre for Quality of Care Research (WOK), University of Nijmegen, The Netherlands.
Qual Life Res. 2001;10(2):141-8. doi: 10.1023/a:1016705615207.
To determine the relationship between functional status and health problems, age and comorbidity in primary care patients.
Patients from 60 general practitioners who visited their general practitioner were recruited and asked to complete a written questionnaire, including a list of 25 health problems and the SF-36 to measure functional status. The response rate was 67% (n = 4,112). Differences between subgroups were tested with p < 0.01.
Poorer functional status which was associated with increased age (except for vitality) and increased co-morbidity. Patients with asthma/ bronchitis/COPD, severe heart disease/infarction, chronic backpain, arthrosis of knees, hips or hands, or an 'other disease' had poorer scores on at least five dimensions of functional status. Patients with hypertension, diabetes mellitus or cancer did not differ from patients without these conditions on more than one dimension of functional status. In the multiple regression analysis age, had a negative effect on functional status (standardised beta-coefficients between -0.03 and -0.34) except for vitality. Co-morbidity had a negative effect on physical role constraints (-0.15) and bodily pain (-0.09). All health problems had effects on dimensions of functional status (coefficients between -0.04 and -0.13). General health and physical dimensions of functional status were better predicted by health problems, age and co-morbidity (between 6.4 and 16.5% of variation explained) than mental dimensions of functional status (between 1.1 and 3.2%).
Higher age was a predictor of poorer functional status, but there was little evidence for an independent effect of co-morbidity on functional status. Health problems had differential impact on functional status among primary care patients.
确定基层医疗患者的功能状态与健康问题、年龄及合并症之间的关系。
招募60位全科医生诊所的就诊患者,并要求他们填写一份书面问卷,其中包括一份25项健康问题清单以及用于测量功能状态的SF-36量表。应答率为67%(n = 4112)。亚组间差异采用p < 0.01进行检验。
功能状态较差与年龄增加(活力维度除外)及合并症增加相关。患有哮喘/支气管炎/慢性阻塞性肺疾病、严重心脏病/心肌梗死、慢性背痛、膝关节、髋关节或手部骨关节炎或“其他疾病”的患者在至少五个功能状态维度上得分较低。患有高血压、糖尿病或癌症的患者与未患这些疾病的患者在功能状态的多个维度上无差异。在多元回归分析中,年龄对功能状态有负面影响(标准化β系数在-0.03至-0.34之间),活力维度除外。合并症对身体角色限制(-0.15)和身体疼痛(-0.09)有负面影响。所有健康问题均对功能状态维度有影响(系数在-0.04至-0.13之间)。与功能状态的心理维度(解释变异在1.1%至3.2%之间)相比,健康问题、年龄和合并症对功能状态的总体健康和身体维度的预测效果更好(解释变异在6.4%至16.5%之间)。
年龄较大是功能状态较差的一个预测因素,但几乎没有证据表明合并症对功能状态有独立影响。健康问题对基层医疗患者的功能状态有不同影响。