CD4（+）调节性T细胞

CD4(+) regulatory T cells.

作者信息

Read S, Powrie F

机构信息

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, OX1 3RE, Oxford, UK.

出版信息

Curr Opin Immunol. 2001 Dec;13(6):644-9. doi: 10.1016/s0952-7915(01)00273-4.

DOI:10.1016/s0952-7915(01)00273-4

PMID:11677084

Abstract

There is now compelling evidence that CD4(+) T cells that specialize in the suppression of immune responses play a key role in the control of immune pathology. Recently, there have been a number of reports that have provided information on the generation of CD4(+) regulatory T cells in the thymus and in the periphery. These cells have also been identified in humans, paving the way for analysis of the function of CD4(+) regulatory T cells in immune-mediated disease.

摘要

现在有令人信服的证据表明，专门抑制免疫反应的CD4(+) T细胞在免疫病理控制中起关键作用。最近，有许多报告提供了关于胸腺和外周CD4(+) 调节性T细胞产生的信息。这些细胞也已在人类中被鉴定出来，为分析CD4(+) 调节性T细胞在免疫介导疾病中的功能铺平了道路。