Perez L H, Gutierrez L A, Vioque J, Torres Y
Hospital Regional de Yarumal, Antioquia, Colombia.
Eur J Epidemiol. 2001;17(3):275-80. doi: 10.1023/a:1017975925554.
The aim of this study was to assess the association between overweight, diabetes, stress and other postulated risk factors for a high blood pressure, on the risk of hypertension.
This matched case-control study included 228 cases randomly selected in a rural adult population in Yarumal--Antioquia, Colombia. For every case, one control, individually matched by age (+/- 5 years), sex and residence, was selected from the general population. Conditional logistic regression was used to estimate odds ratios (OR). Obese people (body mass index (BMI) > or = 30 kg/m2) showed an increased OR of hypertension compared to those with a BMI < 25 kg/m2, OR: 3.83 [95% confidence interval (CI): 1.83-8.00]. A high level of psychological stress was associated with hypertension (measured on a tension-anxiety scale), OR: 5.02 (95% CI: 2.25-11.19). A positive association was also observed for diabetes although it was of borderline significance, OR: 2.58 (95% CI: 0.88-7.55). Having a family member with hypertension or myocardial infarction was related to a higher risk of hypertension (p < 0.05).
This study provides evidence that BMI, stress (feelings of anxiety or tension), and diabetes are independently associated with an increased risk of hypertension in a rural area of Colombia.
本研究旨在评估超重、糖尿病、压力以及其他假定的高血压风险因素与高血压发病风险之间的关联。
这项配对病例对照研究纳入了在哥伦比亚安蒂奥基亚省亚鲁马尔的农村成年人群中随机选取的228例病例。对于每例病例,从普通人群中选取一名对照,按照年龄(±5岁)、性别和居住地进行个体匹配。采用条件逻辑回归来估计比值比(OR)。与体重指数(BMI)<25 kg/m²的人相比,肥胖者(BMI≥30 kg/m²)患高血压的OR值升高,OR:3.83 [95%置信区间(CI):1.83 - 8.00]。高水平的心理压力与高血压相关(通过紧张焦虑量表测量),OR:5.02(95% CI:2.25 - 11.19)。糖尿病也呈现出正相关,尽管具有临界显著性,OR:2.58(95% CI:0.88 - 7.55)。有家庭成员患高血压或心肌梗死与更高的高血压风险相关(p < 0.05)。
本研究提供了证据,表明BMI、压力(焦虑或紧张情绪)和糖尿病在哥伦比亚农村地区与高血压发病风险增加独立相关。