通过酶联免疫吸附测定法检测免疫球蛋白反应来鉴定爱知病毒感染。
Identification of Aichi virus infection by measurement of immunoglobulin responses in an enzyme-linked immunosorbent assay.
作者信息
Yamashita T, Ito M, Tsuzuki H, Sakae K
机构信息
Department of Microbiology, Aichi Prefectural Institute of Public Health, Nagare 7-6, Tsuji-machi, Kita-ku, Nagoya 462-8576, Japan.
出版信息
J Clin Microbiol. 2001 Nov;39(11):4178-80. doi: 10.1128/JCM.39.11.4178-4180.2001.
Abstract
Using inhibitory enzyme-linked immunosorbent assay, seroconversions to Aichi virus were detected in 24 (42.9%) of 56 patients with gastroenteritis in six outbreaks. Virus-specific immunoglobulin M (IgM) was detected in convalescent-phase sera from 7 of 24 patients. Of the other 17 patients, 12 developed a significant increase in both IgA and IgG levels and 5 developed a significant increase in IgG alone.
摘要
采用抑制性酶联免疫吸附测定法，在6次暴发的56例胃肠炎患者中，有24例（42.9%）检测到了对爱知病毒的血清转化。在24例患者的恢复期血清中，7例检测到病毒特异性免疫球蛋白M（IgM）。在其他17例患者中，12例的IgA和IgG水平均显著升高，5例仅IgG水平显著升高。
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