离子液体中钌催化的烯烃复分解反应。

Ruthenium-catalyzed olefin metathesis in ionic liquids.

作者信息

Buijsman R C, van Vuuren E, Sterrenburg J G

机构信息

Lead Discovery Unit, N.V. Organon, P.O. Box 20, 5340 BH Oss, The Netherlands.

出版信息

Org Lett. 2001 Nov 15;3(23):3785-7. doi: 10.1021/ol016769d.

DOI:10.1021/ol016769d

PMID:11700138

Abstract

[reaction--see text] Ionic liquid 1-butyl-3-methylimidazoliumhexafluorophosphate ([bmim]PF(6)) is described as an effective medium for ring-closing metathesis (RCM) using Grubbs catalysts. When [bmim]PF(6) was used as solvent, the RCM showed high conversions and a broad substrate tolerance. [bmim]PF(6) and the ruthenium catalyst were recycled after extraction of the product in the organic phase for at least three cycles.

摘要

[反应——见正文] 离子液体1-丁基-3-甲基咪唑六氟磷酸盐（[bmim]PF₆）被描述为使用格拉布催化剂进行闭环复分解反应（RCM）的有效介质。当[bmim]PF₆用作溶剂时，RCM显示出高转化率和广泛的底物耐受性。在将产物萃取到有机相后，[bmim]PF₆和钌催化剂至少循环使用了三个周期。