Zhu B P, Haines K M, Le T, McGrath-Miller K, Boulton M L
Pregnancy and Infant Health Branch, Division of Reproductive Health, Centers for Disease Control and Prevention, Lansing, MI, USA.
Am J Obstet Gynecol. 2001 Dec;185(6):1403-10. doi: 10.1067/mob.2001.118307.
We evaluated interpregnancy interval in relation to adverse perinatal outcomes and whether the relationship differed by race.
We analyzed the vital statistics data for multiparous white and black women in Michigan who delivered a singleton live birth during the period 1993 through 1998, using stratified and logistic regression techniques.
Among women of both races, the risk for delivering low birth weight, premature, and small-for-gestational-age birth was lowest if the interpregnancy interval was 18 to 23 months. In comparison, among white women, the odds ratios for the 3 outcomes were 1.5, 1.3, and 1.3, respectively, if the interval was <6 months, and 1.9, 1.4, and 1.7, respectively, if the interval was > or =120 months, controlling for other factors. Similarly, among black women, the odds ratios were 1.5, 1.2, and 1.3, respectively, if the interval was <6 months, and 1.6, 1.3, and 1.4, respectively, if the interval was > or =120 months.
An interpregnancy interval of 18 to 23 months is associated with the lowest risk for adverse perinatal outcomes among both white and black women.
我们评估了妊娠间隔与不良围产期结局的关系,以及这种关系是否因种族而异。
我们使用分层和逻辑回归技术,分析了1993年至1998年期间在密歇根州分娩单胎活产的多胎白种和黑种女性的生命统计数据。
在两个种族的女性中,如果妊娠间隔为18至23个月,分娩低体重、早产和小于胎龄儿的风险最低。相比之下,在白种女性中,在控制其他因素的情况下,如果间隔<6个月,这三种结局的比值比分别为1.5、1.3和1.3;如果间隔≥120个月,比值比分别为1.9、1.4和1.7。同样,在黑种女性中,如果间隔<6个月,比值比分别为1.5、1.2和1.3;如果间隔≥120个月,比值比分别为1.6、1.3和1.4。
18至23个月的妊娠间隔与白种和黑种女性不良围产期结局的最低风险相关。