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泛昔洛韦疗法(泛维尔)用于单纯疱疹和带状疱疹感染。

Famiciclovir therapy (famvir) for herpes simplex and herpes zoster infections.

作者信息

Tyring S

机构信息

Departments of Dermatology and Microbiology/Immunology, The University of Texas Medical Branch at Galveston, Texas, USA.

出版信息

Skin Therapy Lett. 2001 Nov;6(12):1-2, 5.

Abstract

Genital herpes simplex and herpes zoster infections are common afflictions that are associated with significant morbidity and a decreased quality of life. Famciclovir (Famvir, Novartis) is an orally administered prodrug of the antiviral agent penciclovir. Its unique pharmacokinetic profile makes it an efficacious, convenient and well-tolerated alternative to the traditionally prescribed acyclovir. Famciclovir is used for the acute treatment and suppressive therapy of recurrent genital herpes as well as for herpes zoster and its debilitating comorbidities. Famiciclovir allows patients to manage or prevent symptoms, thereby significantly improving their quality of life. Its favorable safety profile makes it a good treatment choice for the elderly as well as for immunocompromised patients, including those infected with HIV.

摘要

单纯疱疹病毒感染和带状疱疹感染是常见疾病,会导致严重发病并降低生活质量。泛昔洛韦(泛维尔,诺华公司)是抗病毒药物喷昔洛韦的口服前体药物。其独特的药代动力学特性使其成为传统处方药物阿昔洛韦的有效、便捷且耐受性良好的替代药物。泛昔洛韦用于复发性生殖器疱疹的急性治疗和抑制疗法,以及带状疱疹及其使人虚弱的合并症。泛昔洛韦使患者能够控制或预防症状,从而显著提高他们的生活质量。其良好的安全性使其成为老年人以及免疫功能低下患者(包括感染艾滋病毒的患者)的良好治疗选择。

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