Sal'nikov S N
Klin Med (Mosk). 2001;79(10):42-3.
Efficacy of intravenous drop Nitro Mac (alcoholic solution of nitroglycerin) in acute left ventricular failure and angina of functional class III was investigated in 18 patients aged 42-68 years. 1 ml Nitro Mac solution was diluted in 100 ml isotonic solution once a day (in severe condition twice a day) for 6 days. Nitro Mac relieved anginal attack on infusion minute 3-5 and anginal pain on minute 2. In angina functional class III Nitro Mac completely eliminated anginal attacks in 8 of 10 patients and reduced its number in 2 patients. Exercise tolerance has grown. Oral nitrates' doses could be decreased twice. Side effects were mild. Nitro Mac is recommended for treatment of acute cardiac failure and angina of functional class III as an effective medication.
对18名年龄在42 - 68岁的患者研究了静脉滴注Nitro Mac(硝酸甘油酒精溶液)治疗急性左心室衰竭和Ⅲ级功能性心绞痛的疗效。每天一次将1毫升Nitro Mac溶液稀释于100毫升等渗溶液中(病情严重时每天两次),共治疗6天。Nitro Mac在输注第3 - 5分钟时缓解心绞痛发作,在第2分钟时缓解心绞痛疼痛。在Ⅲ级功能性心绞痛患者中,Nitro Mac使10名患者中的8名完全消除了心绞痛发作,使另外2名患者的发作次数减少。运动耐量有所提高。口服硝酸盐类药物的剂量可减半。副作用轻微。推荐将Nitro Mac作为一种有效药物用于治疗急性心力衰竭和Ⅲ级功能性心绞痛。