微小牛蜱（蜱螨亚纲：硬蜱科）雌蜱体表酯酶的组织化学定位

Histochemical localization of esterases in the integument of the female Boophilus microplus (Acari: Ixodidae) tick.

作者信息

Villarino M A, Waghela S D, Wagner G G

机构信息

Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, College Station 77845-4467, USA.

出版信息

J Med Entomol. 2001 Nov;38(6):780-2. doi: 10.1603/0022-2585-38.6.780.

DOI:10.1603/0022-2585-38.6.780

PMID:11761374

Abstract

The cattle tick Boophilus microplus (Canestrini) is one of the most important ectoparasites affecting tropical cattle with worldwide distribution. Application of organophosphate compounds (OP) is extensively used as a tick control method. However, the appearance of ticks resistant to the OP decreases the therapeutic efficacy of such compounds. Esterases have been implicated as potential biochemical mechanisms for detoxification in B. microplus larvae. We found increased esterase activity in the inner layers of the integument of OP resistant adult female B. microplus ticks as compared with the OP susceptible ticks. We discuss the potential role of these enzymes during acaricide metabolism and propose future research.

摘要

微小牛蜱（Boophilus microplus，Canestrini）是影响热带牛的最重要外寄生虫之一，分布于全球。有机磷化合物（OP）的应用被广泛用作蜱虫控制方法。然而，对OP产生抗性的蜱虫的出现降低了此类化合物的治疗效果。酯酶被认为是微小牛蜱幼虫解毒的潜在生化机制。我们发现，与对OP敏感的蜱虫相比，对OP具有抗性的成年雌性微小牛蜱体表内层的酯酶活性有所增加。我们讨论了这些酶在杀螨剂代谢过程中的潜在作用，并提出了未来的研究方向。