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[胸膜恶性局限性纤维瘤]

[Malignant localized fibrous tumor of the pleura].

作者信息

Franca T, Pinto E, Nogueira F, Velho H V

机构信息

Serviços de Anatomia Patológica e Cirurgia Cardiotorácica, Hospital de Santa Marta, Lisboa.

出版信息

Acta Med Port. 2001 Jul-Aug;14(4):435-40.

Abstract

The authors report a case of a localized fibrous tumour of the pleura with huge proportions of 26 x 14 x 12 cm and 1.25 Kgr of weight, in a 56 year old female patient. The tumour occupied practically the inferior 2/3 of the right pulmonary field and had an unusual insertion in the diaphragmatic parietal pleura. It was non pediculous and had histological features of malignancy. The diagnosis of localized fibrous tumour of the pleura was achieved through observation of the sample obtained by fine needle aspiration. The immunohistochemical study subsequently done on the surgical specimen, confirmed the previous diagnosis. The evaluation of malignancy was based ou the following histological criteria: high cellularity, cellular pleomorphism, mitotic activity (more than four mitotic figures per 10 high power fields), hemorrhagic areas and necrosis.

摘要

作者报告了一例56岁女性患者的胸膜局限性纤维瘤,瘤体尺寸巨大,为26×14×12厘米,重达1.25千克。该肿瘤几乎占据了右肺野的下2/3,且在膈顶胸膜有异常附着。它无蒂,具有恶性组织学特征。通过细针穿刺获取样本观察得以诊断为胸膜局限性纤维瘤。随后对手术标本进行的免疫组化研究证实了先前的诊断。恶性评估基于以下组织学标准:高细胞密度、细胞多形性、有丝分裂活性(每10个高倍视野中有超过4个有丝分裂象)、出血区域和坏死。

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