对源患者进行全天候艾滋病毒检测的备用暴露后预防措施。

Spare post-exposure prophylaxis with round-the-clock HIV testing of the source patient.

作者信息

Greub G, Maziéro A, Bürgisser P, Telenti A, Francioli P

机构信息

Division of Infectious Diseases, University Hospital, Lausanne, Switzerland.

出版信息

AIDS. 2001 Dec 7;15(18):2451-2. doi: 10.1097/00002030-200112070-00014.

DOI:10.1097/00002030-200112070-00014

PMID:11774831

Abstract

After occupational exposures, immediate HIV testing of source patients may avoid the unnecessary use of post-exposure prophylaxis (PEP). Two time periods were compared. Before the availability of 24 h a day immediate testing, PEP was initiated after 12.6% of exposures, compared with 3.7% during the second period. The adjusted relative odds ratio of PEP during the second compared with the first period, was 0.23. The availability of immediate HIV testing limits unnecessary occupational PEP.

摘要

职业暴露后，对源患者进行即时HIV检测可避免不必要地使用暴露后预防（PEP）。对两个时间段进行了比较。在每天24小时即时检测可用之前，12.6%的暴露后启动了PEP，而在第二个时间段这一比例为3.7%。第二个时间段与第一个时间段相比，PEP的调整后相对比值比为0.23。即时HIV检测的可用性限制了不必要的职业性PEP。