Harouna Y, Gamatie Y, Gamatie S, Mounkaila H, Boureima M
Service de chirurgie, Service de pédiatrie, Hôpital national de Niamey-Niger, Faculté des sciences de la santé, Université Abdou Moumouni Dioffo, BP 10896, Niamey, République du Niger.
Bull Soc Pathol Exot. 2000 Jan;93(5):328-30.
Quinine by intramuscular or intrarectal injection has been found to be the best treatment for malaria in Niger, particularly in field health centres where the use of solutions can pose problems. There have been several reports of complications following injections, usually due to technical error or to the toxic side effects of quinine. In our hospital, we treated two such rare complications consisting of a case of coxal osteoarthritis induced by intramuscular injection and a case of anorectal necrotising induced by intrarectal injection. The occurrence of such life-threatening events could be reduced in frequency by teaching health personnel about techniques of quinine administration as well as its dangers.
在尼日尔,肌肉注射或直肠内注射奎宁已被证明是治疗疟疾的最佳方法,特别是在现场医疗中心,使用溶液可能会带来问题。已有数例注射后并发症的报告,通常是由于技术失误或奎宁的毒副作用。在我们医院,我们治疗了两例此类罕见并发症,一例是肌肉注射引起的髋部骨关节炎,另一例是直肠内注射引起的肛门直肠坏死。通过向卫生人员传授奎宁给药技术及其危险性,可以减少此类危及生命事件的发生频率。