由耐喹诺酮大肠杆菌引起的自发性细菌性腹膜炎：类固醇疗法能发挥作用吗？

Spontaneous bacterial peritonitis caused by quinolone-resistant Escherichia coli: could steroid therapy play a role?

作者信息

Cereto Ferran, Genescà Joan, Smithson Alex, González Antonio, Moreno Gina, del Valle Ortiz Oscar, Esteban Rafael, Guardia Jaime

机构信息

Liver Unit, Department of Internal Medicine, Hospital General Universitari Vall d'Hebron, Barcelona, Spain.

出版信息

Eur J Gastroenterol Hepatol. 2002 Jan;14(1):81-3. doi: 10.1097/00042737-200201000-00014.

DOI:10.1097/00042737-200201000-00014

PMID:11782580

Abstract

Prophylaxis with norfloxacin has been shown to be effective in preventing spontaneous bacterial peritonitis (SBP) in liver cirrhosis. This therapy is associated with the appearance of quinolone-resistant Escherichia coli. However, only four cases of SBP caused by quinolone-resistant E. coli have been reported so far. We present four cases of quinolone-resistant E. coli SBP in three patients receiving oral quinolones, and who were on corticosteroid therapy to treat associated disorders.

摘要

已证明使用诺氟沙星进行预防可有效预防肝硬化患者的自发性细菌性腹膜炎（SBP）。这种治疗方法与喹诺酮耐药性大肠杆菌的出现有关。然而，迄今为止仅报告了4例由喹诺酮耐药性大肠杆菌引起的SBP。我们报告了3例接受口服喹诺酮类药物治疗且正在使用皮质类固醇治疗相关疾病的患者发生喹诺酮耐药性大肠杆菌SBP的4个病例。