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颈动脉内膜切除术术后结局的种族差异:来自退伍军人事务部国家外科质量改进计划的证据。

Racial variations in postoperative outcomes of carotid endarterectomy: evidence from the Veterans Affairs National Surgical Quality Improvement Program.

作者信息

Horner Ronnie D, Oddone Eugene Z, Stechuchak Karen M, Grambow Steven C, Gray John, Khuri Shukri F, Henderson William G, Daley Jennifer

机构信息

VA Epidemiologic Research and Information Center, Center for Health Services Research in Primary Care, Stroke QUERI Program, Durham, North Carolina, USA.

出版信息

Med Care. 2002 Jan;40(1 Suppl):I35-43.

Abstract

CONTEXT

Black patients and Hispanic patients receive carotid endarterectomy (CEA) at lower rates than white patients. It is unclear whether worse surgical outcomes are influencing clinical decision-making regarding use of the operation among minority group patients.

OBJECTIVE

To determine if there are racial differences in postoperative outcomes for patients undergoing CEA at Veterans Affairs (VA) medical centers.

DESIGN

Secondary analysis of data from an ongoing, prospective study on surgical quality and outcomes in the VA health care system.

SETTING

One hundred thirty-two VA Medical Centers that were part of the VA National Surgical Quality Improvement Program.

PATIENTS

A cohort of 6551 men (91.4% white, 5.3% black, and 3.3% Hispanic) who had CEA performed between October 1, 1994 and September 30, 1997.

MAIN OUTCOME MEASURES

Primary outcomes were stroke or death and stroke, myocardial infarction (MI), or death within 30 days of the operation.

RESULTS

Thirty-day postoperative rates of stroke or death and of stroke, MI, or death were generally low for all racial/ethnic groups, ranging between 2.6% and 6.5%. Within clinical states that define indications for CEA, rates were also low (1.6% to 3.2%) among asymptomatic patients across racial/ethnic groups. However, among patients with transient ischemic attack (TIA), Hispanic patients had significantly worse outcomes than white patients with a postoperative rate of stroke or death of 10.5% (P < 0.05) and stroke, MI, or death of 13.2% (P < 0.05) compared with 3.1% to 3.5% for white patients. Hispanic patients did not differ from black patients for stroke, death/stroke, death, or MI.

CONCLUSION

Rates of major postoperative complications after CEA are low within the VA and similar across racial/ethnic groups with the possible exception of Hispanic men with TIA. Further investigation of this elevated complication rate among Hispanic men with TIA may be warranted.

摘要

背景

黑人患者和西班牙裔患者接受颈动脉内膜切除术(CEA)的比例低于白人患者。尚不清楚较差的手术结果是否会影响少数群体患者使用该手术的临床决策。

目的

确定在退伍军人事务部(VA)医疗中心接受CEA手术的患者术后结果是否存在种族差异。

设计

对VA医疗保健系统中一项正在进行的关于手术质量和结果的前瞻性研究的数据进行二次分析。

地点

132家VA医疗中心,它们是VA国家手术质量改进计划的一部分。

患者

1994年10月1日至1997年9月30日期间接受CEA手术的6551名男性队列(91.4%为白人,5.3%为黑人,3.3%为西班牙裔)。

主要观察指标

主要结局为卒中或死亡以及术后30天内的卒中、心肌梗死(MI)或死亡。

结果

所有种族/族裔群体术后30天的卒中或死亡率以及卒中、MI或死亡率普遍较低,在2.6%至6.5%之间。在定义CEA适应证的临床状态下,各无症状种族/族裔患者的发生率也较低(1.6%至3.2%)。然而,在短暂性脑缺血发作(TIA)患者中,西班牙裔患者的结局明显比白人患者差,术后卒中或死亡率为10.5%(P<0.05),卒中、MI或死亡率为13.2%(P<0.05),而白人患者为3.1%至3.5%。西班牙裔患者在卒中、死亡/卒中、死亡或MI方面与黑人患者没有差异。

结论

在VA内,CEA术后主要并发症的发生率较低,各种族/族裔群体相似,但患有TIA的西班牙裔男性可能除外。对于患有TIA的西班牙裔男性中这种较高的并发症发生率,可能有必要进行进一步调查。

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