Chen W, Liu Y, Wang N, Guo Y, He M
Department of Cataract, Zhongshan Ophthalnic Center, Sun Yat-Sen University of Medical Sciences, Guangzhou 510060, China.
Chin Med J (Engl). 2001 Dec;114(12):1286-9.
To evaluate the effectiveness and safety of implantation of flexible open-loop anterior chamber intraocular lens (FOAC-IOLs) and scleral fixated posterior chamber intraocular lens (PC-IOLs).
Sixty-eight eyes of 68 patients with implanted intraocular lenses in the absence of posterior capsular support were reviewed retrospectively. According to the type of intraocular lens, patients were classified into two groups. In group I (30 eyes), FOAC-IOLs was implanted primarily or secondarily. In group II (38 eyes), scleral fixated PC-IOLs was implanted primarily or secondarily. By gonioscopy and ultrasound biomicroscopy (UBM), accurate positions of IOLs' haptics and the relationship between the haptics and surrounding tissues were observed postoperatively and used to evaluate the influence of the two types of IOLs on ocular anterior segments. Follow-up was 6 to 20 months.
Best corrected visual acuity of 20/40 or better was achieved in 27 eyes (90.0%) in group I, and 35 eyes (92.1%) in group II and the difference was not statistically significant (P > 0.05). In group I, 23 eyes (76.7%) had a total of 40 complications, while 13 eyes (34.2%) had 19 complications in group II (P < 0.05). Gonioscopy and ultrasound biomicroscopy showed that in group I, all haptics of IOLs contacted with the iris completely and compressed the iris to different degrees, sometimes causing the anterior chamber angles to widen. Anterior synechia of the iris was caused by the haptics of FOAC-IOLs in 12 eyes. Among the 60 IOLs haptics, 39 foot plates of the haptics were properly fixed at the ciliary band; 21 haptics (12 eyes) penetrated through the iris into the stroma of the ciliary body with accompanying recurrent uveitis. In group II, among the 76 IOLs haptics, 52 were adequately fixed in the ciliary sulcus regions, and 8 (8 eyes) were placed below the iris, causing goniosynechia. This type of angle closure was localized, with an open angle on each side of the haptics. The remaining 16 haptics were fixed onto the ciliary crown.
The current sutured mode of scleral fixated PC-IOLs can not ensure that IOLs haptics are placed in the ciliary sulcus. The haptics of FOAC-IOLs compress the iris and may penetrate through the iris into the stroma of the ciliary body. This can cause peripheral iris anterior synechia and chronic recurrent uveitis. The implantation of scleral fixated PC-IOLs is safer and shows better effects than that of FOAC-IOLs.
评估可折叠开环前房型人工晶状体(FOAC-IOL)植入术与巩膜固定后房型人工晶状体(PC-IOL)植入术的有效性和安全性。
回顾性分析68例(68眼)无后囊膜支撑而行人工晶状体植入术患者的临床资料。根据人工晶状体类型将患者分为两组。Ⅰ组(30眼),一期或二期植入FOAC-IOL;Ⅱ组(38眼),一期或二期植入巩膜固定PC-IOL。术后通过房角镜检查和超声生物显微镜(UBM)观察人工晶状体襻的准确位置以及襻与周围组织的关系,以此评估两种人工晶状体对眼前节的影响。随访6~20个月。
Ⅰ组27眼(90.0%)最佳矫正视力达到20/40或更好,Ⅱ组35眼(92.1%),差异无统计学意义(P>0.05)。Ⅰ组23眼(76.7%)共发生40例并发症,Ⅱ组13眼(34.2%)发生19例并发症(P<0.05)。房角镜检查和超声生物显微镜显示,Ⅰ组人工晶状体的所有襻均完全与虹膜接触,并不同程度压迫虹膜,有时导致前房角变宽。12眼因FOAC-IOL襻导致虹膜前粘连。在60个人工晶状体襻中,39个襻的脚板妥善固定于睫状带;21个襻(12眼)穿过虹膜进入睫状体基质,伴有复发性葡萄膜炎。Ⅱ组76个人工晶状体襻中,52个妥善固定于睫状沟区域,8个(8眼)位于虹膜下方,导致房角粘连。这种房角关闭为局限性,襻两侧房角开放。其余16个襻固定于睫状冠。
目前巩膜固定PC-IOL的缝合方式不能确保人工晶状体襻置于睫状沟。FOAC-IOL的襻压迫虹膜,并可能穿过虹膜进入睫状体基质,可导致周边虹膜前粘连和慢性复发性葡萄膜炎。巩膜固定PC-IOL植入术比FOAC-IOL植入术更安全,效果更好。