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韩国的饮食因素与胃癌:一项病例对照研究。

Dietary factors and gastric cancer in Korea: a case-control study.

作者信息

Kim Hyun Ja, Chang Woong Ki, Kim Mi Kyung, Lee Sang Sun, Choi Bo Youl

机构信息

Department of Preventive Medicine, Hanyang University College of Medicine, Seoul, Korea.

出版信息

Int J Cancer. 2002 Feb 1;97(4):531-5. doi: 10.1002/ijc.10111.

Abstract

To assess gastric cancer (GC) risk in relation to dietary intake in Korea, a case-control study was performed. Trained dietitians interviewed 136 patients diagnosed with GC, and the same number of controls were selected by matching sex, age and hospital. A significant decrease in GC risk was observed with increased intake of Baiechu kimchi (prepared with salted Chinese cabbage and red pepper, etc.), Baiechu kimchi-stew, garlic, mushroom and soybean milk. On the contrary, a significant increase in the risk of GC was observed with increased intake of cooked rice with bean, charcoal grilled beef, pollack soup, Kkakduki (a kind of kimchi prepared with salted radish and red pepper, etc.), Dongchimi (a kind of kimchi prepared with radish and a large quantity of salt water) and cooked spinach. In food groups, increased intake of soybean products was associated with decreased risk of GC. Intake of citrus fruits rather than total fruits was shown to have a protective effect on the risk of GC, but was not significant. In this study, intake of total vegetables was shown to have a protective effect, whereas high nitrate-containing vegetables increased the risk of GC. In conclusion, our study suggests that the risk of GC decreased with high consumption of fresh vegetables and fruits, whereas high consumption of foods rich in nitrate and carcinogenic substances produced during the cooking process increased the risk of GC.

摘要

为评估韩国饮食摄入与胃癌(GC)风险的关系,开展了一项病例对照研究。训练有素的营养师对136例确诊为GC的患者进行了访谈,并通过匹配性别、年龄和医院选取了相同数量的对照。随着白泡菜(用腌制的大白菜和红辣椒等制作)、白泡菜炖菜、大蒜、蘑菇和豆浆摄入量的增加,观察到GC风险显著降低。相反,随着豆饭、炭烤牛肉、鳕鱼羹、水萝卜泡菜(用腌制的萝卜和红辣椒等制作的一种泡菜)、东奇米(用萝卜和大量盐水制作的一种泡菜)和煮菠菜摄入量的增加,观察到GC风险显著增加。在食物类别中,大豆制品摄入量增加与GC风险降低相关。摄入柑橘类水果而非全部水果对GC风险具有保护作用,但不显著。在本研究中,蔬菜总摄入量显示具有保护作用,而高硝酸盐含量的蔬菜会增加GC风险。总之,我们的研究表明,高摄入新鲜蔬菜和水果会降低GC风险,而高摄入富含硝酸盐和烹饪过程中产生的致癌物质的食物会增加GC风险。

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