[Effect of escharectomy during burn shock stage on stress response].

OBJECTIVE

To investigate changes in hormones of plasma and the effect of escharectomy during burn shock stage on early stress response after burn.

METHODS

Sixteen male minipigs were subjected to a 35% TBSA III degree burn injury. The burned minipigs were randomly divided into two groups: escharectomy during burn shock stage group (S group) and escharectomy group after burn shock stage (N group). The sequential changes in plasma levels of insulin, glucagon, cortisol, GH, IGF-I, albumin were analyzed.

RESULTS

The serum concentration of insulin, glucagon, cortisol increased to some degree, whereas the serum concentration of GH, IGF-I decreased obviously after burn. As compared with the N group, no significant difference in the serum concentration of glucagon, cortisol, GH, IGF-I, was observed.

CONCLUSIONS

Escharectomy during burn shock stage could not aggravate stress response after burn.