通过天然双链RNA治疗预防NZB/瑞士小鼠对DNA的自发性自身免疫。
Prevention of spontaneous autoimmunity to DNA in NZB/Swiss mice by treatment with natural double-stranded RNA.
作者信息
Rovenský J, Doskocil J, Pekárek J, Borecký L, Zitnan D, Svejcar J
出版信息
Immunology. 1975 Oct;29(4):745-8.
Abstract
Data are presented demonstrating the prevention of spontaneous autoimmune disease in NZB/Swiss mice treated natural double-stranded RNA. The successful treatment of animals was followed both by improvement in clinical manifestations and by the migration inhibition test performed with DNA as antigen. The reasons for the successful employment of natural double-stranded RNA are thought to be in its physicochemical properties.
摘要
数据表明，用天然双链RNA处理的NZB/瑞士小鼠可预防自发性自身免疫疾病。对动物的成功治疗既表现为临床表现的改善，也表现为以DNA为抗原进行的迁移抑制试验结果的改善。天然双链RNA成功应用的原因被认为与其物理化学性质有关。
相似文献
1
Prevention of spontaneous autoimmunity to DNA in NZB/Swiss mice by treatment with natural double-stranded RNA.
Immunology. 1975 Oct;29(4):745-8.
2
3
Spontaneous occurrence of delayed hypersensitivity to DNA in old NZB mice.
Z Immunitatsforsch Exp Klin Immunol. 1975 Nov;150(5):384-8.
4
[Confirmation of delayed hypersensitivity to DNA in NZB mice and in NZB/Swiss F 1 hybrids].
Fysiatr Revmatol Vestn. 1975 Aug;53(4):204-7.
5
Age-dependence of spontaneous delayed hypersensitivity to DNA, antinuclear antibody production and development of glomerulonephritis in NZB mice.
Folia Biol (Praha). 1975;21(4):234-7.
6
Spontaneous delayed hypersensitivity to DNA in NZB mice.
Immunology. 1974 Aug;27(2):241-4.
7
Suppressive oligodeoxynucleotides delay the onset of glomerulonephritis and prolong survival in lupus-prone NZB x NZW mice.
Arthritis Rheum. 2005 Feb;52(2):651-8. doi: 10.1002/art.20810.
8
The contribution of I-Abm12 to phenotypic and functional alterations among T-cell subsets in NZB mice.
J Autoimmun. 1993 Apr;6(2):131-43. doi: 10.1006/jaut.1993.1011.
9
Successful treatment of autoimmunity in (NZB X NZW)F1 mice with cyclosporin and (Nva2)-cyclosporin: I. Reduction of autoantibodies.
Clin Exp Immunol. 1986 May;64(2):225-33.
10
The in vitro and in vivo induction of anti-double-stranded DNA antibodies in normal and autoimmune mice.
J Immunol. 1982 Jan;128(1):409-14.
引用本文的文献
1
Interferon treatment of NZB mice: accelerated progression of autoimmune disease.
Infect Immun. 1978 Sep;21(3):925-30. doi: 10.1128/iai.21.3.925-930.1978.
本文引用的文献
1
A new method for the isolation of deoxyribonucleic acids; evidence on the nature of bonds between deoxyribonucleic acid and protein.
Biochem J. 1957 Jul;66(3):495-504. doi: 10.1042/bj0660495.
2
A new method for the isolation of ribonucleic acids from mammalian tissues.
Biochem J. 1956 Nov;64(3):405-8. doi: 10.1042/bj0640405.
3
The pathogenesis of autoimmunity in New Zealand mice. 3. Factors influencing the formation of anti-nucleic acid antibodies.
Immunology. 1971 Apr;20(4):523-31.
4
A nuclease from animal serum which hydrolyzes double-stranded RNA.
Biochem Biophys Res Commun. 1970 Nov 9;41(3):608-14. doi: 10.1016/0006-291x(70)90056-2.
5
The pathogenesis of autoimmunity in New Zealand mice. II. Acceleration of glomerulonephritis by polyinosinic-polycytidylic acid.
Lab Invest. 1970 Dec;23(6):628-34.
6
The pathogenesis of autoimmunity in New Zealand mice, I. Induction of antinucleic acid antibodies by polyinosinic-polycytidylic acid.
Proc Natl Acad Sci U S A. 1969 Aug;63(4):1102-7. doi: 10.1073/pnas.63.4.1102.
7
Antibodies to ribonucleic acid in systemic lupus erythematosus.
Proc Natl Acad Sci U S A. 1969 Aug;63(4):1108-12. doi: 10.1073/pnas.63.4.1108.
8
Spontaneous delayed hypersensitivity to DNA in NZB mice.
Immunology. 1974 Aug;27(2):241-4.
9
Double-stranded f 2 phage RNA as interferon inducer.
Acta Virol. 1971 Nov;15(6):523.
10
Further implication of murine leukemia-like virs in the disorders of NZB mice.
J Exp Med. 1969 May 1;129(5):1045-62. doi: 10.1084/jem.129.5.1045.
Zotero 插件