Nutting Paul A, Rost Kathryn, Dickinson Miriam, Werner James J, Dickinson Perry, Smith Jeffrey L, Gallovic Beth
Center for Research Strategies, Suite 1150, 225 E 16th Avenue, Denver, CO 80203, USA.
J Gen Intern Med. 2002 Feb;17(2):103-11. doi: 10.1046/j.1525-1497.2002.10128.x.
This study used qualitative and quantitative methods to examine the reasons primary care physicians and nurses offered for their inability to initiate guideline-concordant acute-phase care for patients with current major depression.
Two hundred thirty-nine patients with 5 or more symptoms of depression seeing 12 physicians in 6 primary care practices were randomized to the intervention arm of a trial of the effectiveness of depression treatment. Sixty-six (27.6%) patients identified as failing to meet criteria for guideline-concordant treatment 8 weeks following the index visit were the focus of this analysis.
The research team interviewed the 12 physicians and 6 nurse care managers to explore the major reasons depressed patients fail to receive guideline-concordant acute-phase care. This information was used to develop a checklist of barriers to depression care. The 12 physicians then completed the checklist for each of the 64 patients for whom he or she was the primary care provider. Physicians chose which barriers they felt applied to each patient and weighted the importance of the barrier by assigning a total of 100 points for each patient. Cluster analysis of barrier scores identified naturally occurring groups of patients with common barrier profiles.
The cluster analysis produced a 5-cluster solution with profiles characterized by patient resistance (19 patients, 30.6%), patient noncompliance with visits (15 patients, 24.2%), physician judgment overruled the guideline (12 patients, 19.3%), patient psychosocial burden (8 patients, 12.9%), and health care system problems (8 patients, 12.9%). The physicians assigned 4,707 (75.9%) of the 6,200 weighting points to patient-centered barriers. Physician-centered barriers accounted for 927 (15.0%) and system barriers accounted for 566 (9.1%) of weighting points. Twenty-eight percent of the patients not initiating guideline-concordant acute-stage care went on to receive additional care and met criteria for remission at 6 months, with no statistical difference across the 5 patient clusters.
Current interventions fail to address barriers to initiating guideline-concordant acute-stage care faced by more than a quarter of depressed primary care patients. Physicians feel that barriers arise most frequently from factors centered with the patients, their psychosocial circumstances, and their attitudes and beliefs about depression and its care. Physicians less frequently make judgments that overrule the guidelines, but do so when patients have complex illness patterns. Further descriptive and experimental studies are needed to confirm and further examine barriers to depression care. Because few untreated patients improve without acute-stage care, additional work is also needed to develop new intervention components that address these barriers.
本研究采用定性和定量方法,探究初级保健医生和护士对于无法为当前患有重度抑郁症的患者启动符合指南的急性期护理所给出的原因。
在6家初级保健机构中,12名医生诊治的239名有5种或更多抑郁症状的患者被随机分配至一项抑郁症治疗有效性试验的干预组。在首次就诊8周后,66名(27.6%)被确定未达到符合指南治疗标准的患者成为本分析的重点。
研究团队采访了12名医生和6名护士护理经理,以探究抑郁症患者未能接受符合指南的急性期护理的主要原因。这些信息被用于制定抑郁症护理障碍清单。然后,12名医生针对其作为初级保健提供者的64名患者中的每一位完成该清单。医生选择他们认为适用于每位患者的障碍,并通过为每位患者总共分配100分来权衡障碍的重要性。对障碍得分进行聚类分析,确定了具有共同障碍特征的自然形成的患者组。
聚类分析得出了一个5类解决方案,其特征分别为患者抵触(19名患者,30.6%)、患者不遵守就诊安排(15名患者,24.2%)、医生的判断推翻了指南(12名患者,19.3%)、患者的心理社会负担(8名患者,12.9%)以及医疗保健系统问题(8名患者,12.9%)。医生将6200个加权分中的4707个(75.9%)分配给了以患者为中心的障碍。以医生为中心的障碍占加权分的927个(15.0%),系统障碍占566个(9.1%)。28%未启动符合指南的急性期护理的患者继续接受了额外护理,并在6个月时达到缓解标准,5个患者组之间无统计学差异。
当前的干预措施未能解决超过四分之一的初级保健抑郁症患者在启动符合指南的急性期护理时所面临的障碍。医生认为障碍最常源于与患者相关的因素、他们的心理社会状况以及他们对抑郁症及其护理的态度和信念。医生较少做出推翻指南的判断,但在患者病情复杂时会这样做。需要进一步的描述性和实验性研究来确认并进一步研究抑郁症护理的障碍。由于很少有未接受治疗的患者在没有急性期护理的情况下好转,因此还需要开展更多工作来开发解决这些障碍的新干预措施。