Crosson K, Eisner E, Brown C, Ter Maat J
Office of Education and Special Initiatives, National Cancer Institute, Bethesda, Maryland 20892, USA.
J Cancer Educ. 2001 Winter;16(4):188-92. doi: 10.1080/08858190109528771.
Participation of patients in cancer clinical trials is disappointingly low and several physician-based factors are thought to be responsible.
In 1998-1999, the National Cancer Institute (NCI) conducted a probability survey of three primary care physician groups to gain a better understanding of the barriers to clinical-trial patient accrual from their perspective.
Findings from this survey of 706 primary care physicians indicate that the vast majority (98%) refer their patients with cancer to a specialist for cancer treatment and rarely bring up the topic of cancer clinical trials. Frequently cited reasons for not mentioning clinical trials are preferring to leave that discussion to the oncologist (41%) and being unaware of any clinical trials that may be available for the patient (37%).
Primary care physicians may represent an important untapped resource for introducing the concept of clinical trials as an option to newly diagnosed cancer patients.
患者参与癌症临床试验的比例低得令人失望,一些基于医生的因素被认为是造成这一现象的原因。
1998年至1999年,美国国立癌症研究所(NCI)对三个初级保健医生群体进行了概率抽样调查,以便从他们的角度更好地了解临床试验患者招募的障碍。
对706名初级保健医生的调查结果表明,绝大多数(98%)将癌症患者转诊给专科医生进行癌症治疗,很少提及癌症临床试验的话题。不提及临床试验的常见原因是更愿意将该讨论留给肿瘤学家(41%)以及不知道患者可能适用的任何临床试验(37%)。
初级保健医生可能是向新诊断的癌症患者介绍临床试验概念作为一种选择的重要未开发资源。