单胺能神经毒素：它们具有选择性吗？

Monoaminergic neurotoxins: are they selective?

作者信息

Bloom F E

出版信息

J Neural Transm. 1975;37(3):183-7. doi: 10.1007/BF01670127.

Abstract

Introduction of 6-hydroxydopamine into the cerebrospinal fluid produces a selective destruction of adrenergic pathways. However, the selectivity of interstitial injections of 6-hydroxydopamine for catecholamine elements is critically dependent upon the dose and volume of injection must be evaluated by biochemical and cytochemical indices.

摘要

将6-羟基多巴胺注入脑脊液会导致肾上腺素能通路的选择性破坏。然而，6-羟基多巴胺间质注射对儿茶酚胺元件的选择性严重依赖于注射剂量，且注射体积必须通过生化和细胞化学指标进行评估。