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嗜睡、意识周期三联征与爱泼沃斯嗜睡量表。

Sleepiness, troika of consciousness cycle, and the Epworth sleepiness scale.

作者信息

George P T

出版信息

Sleep Breath. 2001 Dec;5(4):181-91. doi: 10.1007/s11325-001-0181-7.

Abstract

Excessive daytime sleepiness (EDS) is an important indicator when diagnosing sleep-disordered breathing and evaluating its treatment results. However, there appears to be some confusion as to what exactly is sleepiness; Dorland's Illustrated Medical Dictionary does not help. The medical literature was reviewed in order to assemble a schematic model that would suggest a definition of sleepiness and how it can be measured. The derived model is entitled the troika of consciousness cycle (TCC). It assumes that the presence of wakefulness, nonrapid eye movement sleep (NREMS), and rapid eye movement sleep (REMS) is determined by the interactions of four drives: two promoting wakefulness and one each for the two sleep states. The TCC illustrates that inadequate sleep results in sleep debt, but that sleepiness is determined solely by the nearness of the secondary wake drive line to the NREMS drive line. Contact of these lines indicates dozing, a change in consciousness state, an observable event. The probability of this event may be defined as objective sleepiness; this is what the Epworth sleepiness scale (ESS) attempts to measure. Studies indicate that the ESS can determine EDS with greater sensitivity and selectivity than either the multiple sleep latency test or the maintenance of wakefulness test.

摘要

日间过度嗜睡(EDS)是诊断睡眠呼吸障碍及评估其治疗效果的一项重要指标。然而,对于究竟什么是嗜睡,似乎存在一些混淆;《多兰氏 Illustrated 医学词典》对此并无帮助。为了构建一个能给出嗜睡定义及其测量方法的示意图模型,我们对医学文献进行了综述。推导得出的模型名为意识周期三元组(TCC)。它假定清醒、非快速眼动睡眠(NREMS)和快速眼动睡眠(REMS)的存在是由四种驱动力的相互作用决定的:两种促进清醒,另外两种分别对应两种睡眠状态各一种。TCC 表明睡眠不足会导致睡眠债,但嗜睡仅由次级清醒驱动力线与 NREMS 驱动力线的接近程度决定。这两条线的接触表明打瞌睡,即意识状态的改变,这是一个可观察到的事件。该事件的概率可定义为客观嗜睡;这正是爱泼华嗜睡量表(ESS)试图测量的内容。研究表明,与多次睡眠潜伏期试验或清醒维持试验相比,ESS 能以更高的敏感性和选择性来确定 EDS。

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