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1989年至1996年根治性前列腺切除术率的升降情况。

Rise and fall of radical prostatectomy rates from 1989 to 1996.

作者信息

Sheikh Kazim, Bullock Claudia

机构信息

U.S. Department of Health and Human Services, Centers for Medicare & Medicaid, Kansas City, Missouri 64106, USA.

出版信息

Urology. 2002 Mar;59(3):378-82. doi: 10.1016/s0090-4295(01)01588-6.

Abstract

OBJECTIVES

To describe the changes in the rates of radical prostatectomy procedures, prostate-specific antigen (PSA) screening tests among Medicare beneficiaries, and the incidence of prostate cancer in the United States and to explain the exaggerated increase and decrease in the frequency of radical prostatectomy from 1989 to 1996.

METHODS

Medicare claims data on radical prostatectomy procedures and screening PSA tests and the National Cancer Institute's Surveillance, Epidemiology, and End Results prostate cancer incidence data were used to estimate the rates of PSA testing and radical prostatectomy among Medicare beneficiaries aged 65 to 74 years and 75 years and older (population rates). The age-specific true rates of the procedure were also estimated for the incident cases of prostate cancer (the population at risk of undergoing radical prostatectomy) among the beneficiaries.

RESULTS

The PSA test, prostate cancer incidence, and radical prostatectomy rates increased from 1989 to 1992. Thereafter, the incidence of prostate cancer, and the population and true rates of radical prostatectomy declined. The percentage of increase and decrease in the population rate of radical prostatectomy was approximately twice that in its true rate.

CONCLUSIONS

The radical prostatectomy rates based on all Medicare beneficiaries grossly exaggerated the changes in the use of the procedure. Where possible, true rates, using the population at risk as the denominator, should be used in the studies of diagnostic and therapeutic procedures, complications, and adverse effects.

摘要

目的

描述美国根治性前列腺切除术的手术率、医疗保险受益人中前列腺特异性抗原(PSA)筛查检测情况以及前列腺癌的发病率变化,并解释1989年至1996年根治性前列腺切除术频率的过度增减情况。

方法

利用医疗保险关于根治性前列腺切除术手术和PSA筛查检测的理赔数据,以及美国国立癌症研究所的监测、流行病学和最终结果前列腺癌发病率数据,估算65至74岁以及75岁及以上医疗保险受益人中PSA检测率和根治性前列腺切除术率(总体率)。还针对受益人中前列腺癌发病病例(有接受根治性前列腺切除术风险的人群)估算了该手术的年龄特异性实际发生率。

结果

1989年至1992年期间,PSA检测、前列腺癌发病率和根治性前列腺切除术率均有所上升。此后,前列腺癌发病率以及根治性前列腺切除术的总体率和实际发生率均下降。根治性前列腺切除术总体率的增减百分比约为其实际发生率的两倍。

结论

基于所有医疗保险受益人的根治性前列腺切除术率严重夸大了该手术使用情况的变化。在可能的情况下,在诊断和治疗程序、并发症及不良反应的研究中应使用以有风险人群为分母的实际发生率。

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