Chen Jarvis T, Krieger Nancy, Van Den Eeden Stephen K, Quesenberry Charles P
Department of Health and Social Behavior, Harvard School of Public Health, Boston, Massachusetts 02122, USA.
Environ Health Perspect. 2002 Apr;110 Suppl 2(Suppl 2):211-6. doi: 10.1289/ehp.02110s2211.
Although allergic diseases such as asthma and hay fever are a major cause of morbidity in industrialized countries, most studies have focused on patterns of prevalence among children and adolescents, with relatively few studies on variations in prevalence by race/ethnicity and socioeconomic position among adults. Our study examined racial/ethnic and socioeconomic patterns in the prevalence of asthma overall, asthma with hay fever, asthma without hay fever, and hay fever overall, in a population of 173,859 women and men in a large prepaid health plan in northern California. Using education as a measure of socioeconomic position, we found evidence of a positive gradient for asthma with hay fever with increasing level of education but an inverse gradient for asthma without hay fever. Hay fever was also strongly associated with education. Compared with their White counterparts, Black women and men were more likely to report asthma without hay fever, and Black women were less likely to have asthma with hay fever. Asian men were also more likely to report asthma with hay fever, and Asian women and men were much more likely to have hay fever. Racial/ethnic disparities in prevalence of allergic diseases were largely independent of education. We discuss implications for understanding these social inequalities in allergic disease risk in relation to possible differences in exposure to allergens and determinants of immunologic susceptibility and suggest directions for future research.
尽管哮喘和花粉症等过敏性疾病是工业化国家发病的主要原因,但大多数研究都集中在儿童和青少年中的患病率模式,而针对成年人中按种族/族裔和社会经济地位划分的患病率差异的研究相对较少。我们的研究调查了加利福尼亚州北部一个大型预付健康计划中173,859名男女群体中哮喘总体、伴有花粉症的哮喘、不伴有花粉症的哮喘以及花粉症总体的种族/族裔和社会经济模式。以教育程度作为社会经济地位的衡量标准,我们发现伴有花粉症的哮喘患病率随着教育程度的提高呈正梯度变化的证据,但不伴有花粉症的哮喘患病率呈负梯度变化。花粉症也与教育程度密切相关。与白人相比,黑人男女更有可能报告患有不伴有花粉症的哮喘,而黑人女性患伴有花粉症哮喘的可能性较小。亚洲男性也更有可能报告患有伴有花粉症的哮喘,亚洲女性和男性患花粉症的可能性要大得多。过敏性疾病患病率的种族/族裔差异在很大程度上与教育程度无关。我们讨论了在理解过敏性疾病风险方面这些社会不平等与接触过敏原的可能差异以及免疫易感性决定因素之间的关系,并提出了未来研究的方向。