MacKenzie Ellen J, Bosse Michael J, Kellam James F, Burgess Andrew R, Webb Lawrence X, Swiontkowski Marc F, Sanders Roy, Jones Alan L, McAndrew Mark P, Patterson Brendan, McCarthy Melissa L, Rohde Charles A
Department of Orthopaedics, University of Minnesota, Minneapolis, Minnesota 55455, USA.
J Trauma. 2002 Apr;52(4):641-9. doi: 10.1097/00005373-200204000-00005.
Factors thought to influence the decision for limb salvage include injury severity, physiologic reserve of the patient, and characteristics of the patient and their support system.
Eligible patients were between the ages of 16 and 69 with Gustilo type IIIB and IIIC tibial fractures, dysvascular limbs resulting from trauma, type IIIB ankle fractures, or severe open midfoot or hindfoot injuries. Data collected at enrollment relevant to the decision-making process included injury characteristics and its treatment, and the nature and severity of other injuries. Logistic regression and stepwise modeling were used to determine the effect of each covariate on the variable salvage/ amputation.
Of 527 patients included in the analysis, 408 left the hospital with a salvaged limb. Of the 119 amputations performed, 55 were immediate and 64 were delayed. The multivariate analysis confirmed the bivariate analysis: all injury characteristics remained significant predictors of limb status with the exception of bone loss; and soft tissue injury and absence of plantar sensation were the most important factors in accounting for model validity.
Soft tissue injury severity has the greatest impact on decision making regarding limb salvage versus amputation.
被认为影响保肢决策的因素包括损伤严重程度、患者的生理储备以及患者及其支持系统的特征。
符合条件的患者年龄在16至69岁之间,患有Gustilo IIIB型和IIIC型胫骨骨折、创伤导致的肢体血运障碍、IIIB型踝关节骨折或严重的开放性中足或后足损伤。在入组时收集的与决策过程相关的数据包括损伤特征及其治疗情况,以及其他损伤的性质和严重程度。采用逻辑回归和逐步建模来确定每个协变量对保肢/截肢变量的影响。
纳入分析的527例患者中,408例出院时肢体得以保留。在119例截肢手术中,55例为即刻截肢,64例为延迟截肢。多变量分析证实了双变量分析的结果:除骨缺损外,所有损伤特征仍然是肢体状况的重要预测因素;软组织损伤和足底感觉缺失是模型有效性的最重要因素。
软组织损伤严重程度对保肢与截肢决策的影响最大。