Bowling David M
Massachusetts Eye and Ear Infirmary, Department of Otolaryngology, and Harvard Medical School, Boston 02180, USA.
Otolaryngol Head Neck Surg. 2002 Mar;126(3):316-20. doi: 10.1067/mhn.2002.122386.
The study goal was to evaluate the effectiveness of argon beam coagulation (ABC) in the prevention of post-tonsillectomy hemorrhage. ABC provides monopolar coagulation by arcing ionized argon gas to the target tissue; it is not a laser.
Two consecutive studies were performed as follows. In the first, a retrospective analysis of post-tonsillectomy bleeding in 344 patients was conducted. Final tonsil fossa hemostasis was achieved with ABC (257 patients) or with electrocoagulation (EC) (87 patients). In the second, a prospective, randomized, patient-blind study of post-tonsillectomy bleeding was conducted in 88 patients. Final hemostasis was achieved using ABC in one fossa and EC in the other fossa, with the sides chosen at random.
Post-tonsillectomy hemorrhage was defined as the expectoration of fresh blood, as opposed to blood-streaked saliva. The rates of bleeding for the 2 studies were as follows. In study 1 for EC, 20% for adults, 6.5% for children, and 10.3% for total; for ABC, 4.7% for adults, 0.6% for children, and 1.9% for total. In study 2 for EC, 19.2% for adults, 1.6% for children, and 6.8% for total; for ABC, 7.7% for adults, 0.0% for children, and 1.1% for total. The rates of hospital admission for observation or reoperation to treat the bleeding in study 1 for EC were 8% for adults, 6.5% for children, and 6.9% for total; for ABC, 1.2% for adults, 0.6% for children, and 0.7% for total. Corresponding rates for study 2 for EC were 15.4% for adults, 1.6% for children, and 5.7% for total; for ABC, 3.8% for adults, 0.0% for children, and 1.1% for total.
ABC is more effective than EC for hemostasis after tonsillectomy. The costs of ABC use vs the savings achieved from reduced bleeding are discussed.
本研究的目标是评估氩离子束凝固术(ABC)在预防扁桃体切除术后出血方面的有效性。ABC通过将电离氩气电弧作用于目标组织来提供单极凝固;它不是激光。
连续进行了两项研究,具体如下。第一项研究,对344例扁桃体切除术后出血患者进行回顾性分析。最终扁桃体窝止血采用ABC(257例患者)或电凝术(EC)(87例患者)。第二项研究,对88例患者进行前瞻性、随机、患者盲法扁桃体切除术后出血研究。一侧扁桃体窝采用ABC止血,另一侧采用EC止血,两侧随机选择。
扁桃体切除术后出血定义为咳出新鲜血液,而非带血丝的唾液。两项研究的出血率如下。在研究1中,EC组成人出血率为20%,儿童为6.5%,总体为10.3%;ABC组成人出血率为4.7%,儿童为0.6%,总体为1.9%。在研究2中,EC组成人出血率为19.2%,儿童为1.6%,总体为6.8%;ABC组成人出血率为7.7%,儿童为0.0%,总体为1.1%。在研究1中,因出血需住院观察或再次手术治疗的EC组成人比例为8%,儿童为6.5%,总体为6.9%;ABC组成人比例为1.2%,儿童为0.6%,总体为0.7%。研究2中,EC组相应的成人比例为15.4%,儿童为1.6%,总体为5.7%;ABC组成人比例为3.8%,儿童为0.0%,总体为1.1%。
扁桃体切除术后止血,ABC比EC更有效。文中讨论了使用ABC的成本与因减少出血所节省的费用。