内源性雌激素在自主神经系统调节中作用的证据。
Evidence of a role of endogenous estrogen in the modulation of autonomic nervous system.
作者信息
Mercuro G, Podda A, Pitzalis L, Zoncu S, Mascia M, Melis G B, Rosano G M
机构信息
Institute of Cardiology, and Department of Obstetrics and Gynecology, University of Cagliari, Sardinia, Italy.
出版信息
Am J Cardiol. 2000 Mar 15;85(6):787-9, A9. doi: 10.1016/s0002-9149(99)00865-6.
We studied heart rate variability in 14 healthy women before and after oophorectomy compared with 14 matched women who underwent hysterectomy with ovarian conservation. Surgical menopause induced a decline in cardiac vagal modulation with a shift toward sympathetic hyperactivity. Recovery of the baseline condition after 3 months of estrogen replacement therapy in oophorectomized women suggests a role of estrogen in the autonomic nervous control of the cardiovascular system.
我们对14名健康女性在卵巢切除术前和术后的心率变异性进行了研究，并与14名接受了保留卵巢的子宫切除术的匹配女性进行了比较。手术绝经导致心脏迷走神经调节功能下降，并向交感神经活动亢进转变。卵巢切除术后的女性在接受3个月雌激素替代治疗后恢复到基线状态，这表明雌激素在心血管系统的自主神经控制中发挥作用。
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