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[在科特迪瓦阿比让一名处于免疫抑制早期阶段感染HIV-1的成人中的杆菌性血管瘤病]

[Bacillary angiomatosis in an adult infected with HIV-1 at an early stage of immunodepression in Abidjan, Côte d'Ivoire].

作者信息

Minga K A, Gberi I, Boka M B, Gourvellec G, Abo Y, Dohoun L, Abe H, Ekra D, Bonard D, Danel C, Huet C, Salamon R, Bondurand A, N'Dri-Yoman T, Anglaret X

机构信息

Centre national de transfusion sanguine et FONSIDA, BP V15, Abidjan, Côte d'Ivoire.

出版信息

Bull Soc Pathol Exot. 2002 Mar;95(1):34-6.

Abstract

Human immunodeficiency virus (HIV)-associated bacillary angiomatosis has rarely been described in Africa. We report here the first case in Côte d'Ivoire. Although in industrialised countries bacillary angiomatosis has been described in patients with low CD4 count, this episode occurred in the first year following HIV-seroconversion in an adult patient with more than 500 CD4 cells per cubic millimetre. Symptoms rapidly and totally disappeared under erythromycin treatment, although with a relapse two years after the end of the first episode. In Africa where people living with HIV often present chronic cutaneous lesions, bacillary angiomatosis may be under-diagnosed. Bacillary angiomatosis must be systematically considered in face of lesions similar to Kaposi's sarcoma. Improving knowledge on symptoms of bacillary angiomatosis in Africa should lead to better treatment and a better estimation of its true frequency which may be underestimated.

摘要

人类免疫缺陷病毒(HIV)相关的杆菌性血管瘤在非洲鲜有报道。我们在此报告科特迪瓦的首例病例。尽管在工业化国家,杆菌性血管瘤多见于CD4细胞计数低的患者,但该病例发生在一名成年患者HIV血清转换后的第一年,其每立方毫米CD4细胞计数超过500个。在红霉素治疗下,症状迅速完全消失,尽管在首次发作结束两年后复发。在非洲,感染HIV的人常出现慢性皮肤病变,杆菌性血管瘤可能未得到充分诊断。面对类似卡波西肉瘤的病变时,必须系统地考虑杆菌性血管瘤。提高对非洲杆菌性血管瘤症状的认识应有助于更好地治疗,并更准确地估计其实际发病率,目前其发病率可能被低估。

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