间歇性跛行患者运动期间小腿肌肉的血氧饱和度测量
Oxygen saturation measurement of calf muscle during exercise in intermittent claudication.
作者信息
Komiyama T, Onozuka A, Miyata T, Shigematsu H
机构信息
Division of Vascular Surgery, Department of Surgery, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8655, Japan.
出版信息
Eur J Vasc Endovasc Surg. 2002 May;23(5):388-92. doi: 10.1053/ejvs.2002.1645.
OBJECTIVES
to evaluate the oxygen saturation of the calf muscle measured by means of spatially resolved spectroscopy (SRS) in claudicants.
METHODS
a total of 150 legs in 84 consecutive patients with calf claudication were studied by SRS. Oxygen saturation (SmO(2)) and the relative changes in oxygenated haemoglobin (HbO(2)) and deoxygenated haemoglobin (Hb) of the gastrocnemius muscle were measured during a treadmill walking test (2.4 km/h, 12%, 5 min).
RESULTS
exercise was associated with a decrease in HbO(2) and an increase in Hb. There was no difference in SmO(2) at rest among all groups. The decrease oxygen saturation correlated well with the severity of symptoms of IC.
CONCLUSION
muscle oxygen saturation measurement by SRS can be used clinically to provide objective information regarding the severity of IC.
目的
评估采用空间分辨光谱法（SRS）测量的跛行患者小腿肌肉的氧饱和度。
方法
通过SRS对84例连续性小腿跛行患者的150条腿进行研究。在跑步机行走试验（2.4 km/h，12%坡度，5分钟）期间，测量腓肠肌的氧饱和度（SmO₂）以及氧合血红蛋白（HbO₂）和脱氧血红蛋白（Hb）的相对变化。
结果
运动与HbO₂降低和Hb升高相关。所有组在静息时的SmO₂无差异。氧饱和度降低与间歇性跛行（IC）症状的严重程度密切相关。
结论
SRS测量肌肉氧饱和度可在临床上用于提供有关IC严重程度的客观信息。
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