泊沙康唑治疗尖端赛多孢菌脑脓肿
Treatment of Scedosporium apiospermum brain abscesses with posaconazole.
作者信息
Mellinghoff Ingo K, Winston Drew J, Mukwaya Geoffrey, Schiller Gary J
机构信息
Division of Hematology-Oncology, Department of Medicine, University of California Los Angeles School of Medicine, Los Angeles, CA, 90095, USA.
出版信息
Clin Infect Dis. 2002 Jun 15;34(12):1648-50. doi: 10.1086/340522. Epub 2002 May 16.
DOI:10.1086/340522
PMID:12032903
Abstract
A 41-year-old man with acute lymphoblastic leukemia developed multiple Scedosporium apiospermum brain abscesses. The infection progressed despite neurosurgical drainage and treatment with itraconazole, amphotericin B, and ketoconazole, but the brain abscesses completely resolved after treatment with posaconazole alone.
摘要
一名41岁的急性淋巴细胞白血病男性患者发生了多发性尖端赛多孢菌脑脓肿。尽管进行了神经外科引流，并使用伊曲康唑、两性霉素B和酮康唑治疗，但感染仍在进展，不过在单独使用泊沙康唑治疗后，脑脓肿完全消退。
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