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酒精性肝病的发病机制——最新进展

Pathogenesis of alcoholic liver disease--recent advances.

作者信息

Nanji Amin A, Su Grace L, Laposata Michael, French Samuel W

机构信息

Department of Pathology and Center for the Study of Liver Diseases, The University of Hong Kong and Queen Mary Hospital.

出版信息

Alcohol Clin Exp Res. 2002 May;26(5):731-6.

Abstract

The article summarizes the proceedings of a symposium on recent advances in research on the pathogenesis of alcoholic liver disease at the 2001 RSA meeting in Montreal, Canada. The chairs were Amin A. Nanji and Samuel W. French. The presentations were (1) Role of inflammatory mediators in alcoholic liver injury by Amin A. Nanji, (2) Role of endotoxin, lipopolysaccharide binding protein, CD14 and Toll receptors in alcoholic liver injury by Grace Su, (3) Fatty acid ethyl esters: toxicity, metabolism and markers of ethanol intake by Michael Laposata, and (4) Cyclic changes in gene expression when rats are fed alcohol at a constant rate by Samuel W. French.

摘要

本文总结了在加拿大蒙特利尔举行的2001年RSA会议上关于酒精性肝病发病机制研究最新进展研讨会的会议记录。会议主席是阿明·A·南吉和塞缪尔·W·弗伦奇。发言内容包括:(1)阿明·A·南吉所做的“炎症介质在酒精性肝损伤中的作用”;(2)格蕾丝·苏所做的“内毒素、脂多糖结合蛋白、CD14和Toll受体在酒精性肝损伤中的作用”;(3)迈克尔·拉波萨塔所做的“脂肪酸乙酯:毒性、代谢及乙醇摄入标志物”;(4)塞缪尔·W·弗伦奇所做的“大鼠持续摄入酒精时基因表达的周期性变化”。

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