Jones G, Cooley H M
Menzies Centre for Population Health Research, Hobart, Tasmania, Australia.
J Paediatr Child Health. 2002 Jun;38(3):278-83. doi: 10.1046/j.1440-1754.2002.00811.x.
To document symptomatic fracture incidence in those aged under 50 years of age.
Fractures were ascertained from X-ray reports containing the word 'fracture' from all radiology providers for the geographically defined population of southern Tasmania (n = 165 175) for the period 1 July 1997 to 30 June 1999.
In the 2-year study frame there were 2943 fractures in 164 730 person years in males and 1348 fractures in 165 620 person years in females. This represents a fracture incidence of 1787 per 100 000 person years in males and 819 per 100 000 person years in females. Peak fracture incidence was 10-14 years in females and 15-19 years in males although different fracture types had varying peak incidence suggesting different fracture-specific causes. The most common fractures were those of the hand (24%), forearm (17%), wrist (10%) and foot (9%). All fractures (including vertebral) were more common in males with relative risks ranging from 1.34 to 4.50. The estimated probability of at least one fracture between birth and 50 years of age was 59% for males and 34% for females.
There are threefold as many fractures in this age group compared to those due to osteoporosis in the elderly in any given year. More research priority needs to be given to understanding the causes of these fractures so that preventive strategies can be formulated.
记录50岁以下人群有症状骨折的发生率。
从1997年7月1日至1999年6月30日,在塔斯马尼亚南部地理区域定义的人群(n = 165175)中,从所有放射科供应商提供的包含“骨折”一词的X线报告中确定骨折情况。
在为期2年的研究框架内,男性164730人年中有2943例骨折,女性165620人年中有1348例骨折。这代表男性骨折发生率为每10万人年1787例,女性为每10万人年819例。女性骨折发生率峰值在10 - 14岁,男性在15 - 19岁,尽管不同骨折类型的峰值发生率不同,提示有不同的骨折特异性病因。最常见的骨折部位是手部(24%)、前臂(17%)、腕部(10%)和足部(9%)。所有骨折(包括椎体骨折)在男性中更常见,相对风险范围为1.34至4.50。出生至50岁至少发生一次骨折的估计概率,男性为59%,女性为34%。
在任何给定年份,该年龄组的骨折数量是老年人骨质疏松性骨折数量的三倍。需要更多研究重点来了解这些骨折的病因,以便制定预防策略。