慕尼黑基于服务的肌张力障碍调查。

Service-based survey of dystonia in munich.

作者信息

Castelon Konkiewitz E, Trender-Gerhard I, Kamm C, Warner T, Ben-Shlomo Y, Gasser T, Conrad B, Ceballos-Baumann A O

机构信息

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Germany.

出版信息

Neuroepidemiology. 2002 Jul-Aug;21(4):202-6. doi: 10.1159/000059525.

DOI:10.1159/000059525

PMID:12065883

Abstract

We performed a service-based epidemiological study of dystonia in Munich, Germany. Due to favourable referral and treatment patterns in the Munich area, we could provide confident data from dystonia patients seeking botulinum toxin treatment. A total of 230 patients were ascertained, of whom 188 had primary dystonia. Point prevalence ratios were estimated to be 10.1 (95% confidence interval 8.4-11.9) per 100,000 for focal and 0.3 (0.0-0.6) for generalised primary dystonia. The most common focal primary dystonias were cervical dystonia with 5.4 (4.2-6.7) and essential blepharospasm with 3.1 (2.1-4.1) per 100,000 followed by laryngeal dystonia (spasmodic dysphonia) with 1.0 (0.4-1.5) per 100,000.

摘要

我们在德国慕尼黑进行了一项基于服务的肌张力障碍流行病学研究。由于慕尼黑地区良好的转诊和治疗模式，我们能够提供来自寻求肉毒杆菌毒素治疗的肌张力障碍患者的确切数据。共确定了230名患者，其中188名患有原发性肌张力障碍。局灶性原发性肌张力障碍的点患病率估计为每10万人10.1（95%置信区间8.4 - 11.9），全身性原发性肌张力障碍为每10万人0.3（0.0 - 0.6）。最常见的局灶性原发性肌张力障碍是颈部肌张力障碍，每10万人中有5.4（4.2 - 6.7）例，原发性眼睑痉挛每10万人中有3.1（2.1 - 4.1）例，其次是喉肌张力障碍（痉挛性发声障碍），每10万人中有1.0（0.4 - 1.5）例。