抗生素预防下手术部位感染的发生率及危险因素
Rate and risk factors of surgical site infections with antibiotic prophylaxis.
作者信息
Raja'a Yahia A, Salam Aisha R, Salih Yahia A, Salman Mosleh S, Al-Baseer Lyla S, Al-Kirshi Najib A, Al-Jalal Najib S
机构信息
Department of Community Medicine, Faculty of Medicine and Health Sciences, Sana'a University, Republic of Yemen.
出版信息
Saudi Med J. 2002 Jun;23(6):672-4.
OBJECTIVE
This study is aimed at determining the incidence of surgical site infections, with antibiotic use. Furthermore, to correlate infection with type of operations, length of intervention, number of stitches, pre-operative hospitalization, age and sex of the patient.
METHODS
All Yemeni patients (N=601) who underwent surgical intervention, with preoperative antibiotic prophylaxis, at Al-Kuwait University Hospital, Sana'a, Republic of Yemen, during 1st August 2000 through to 30th November 2000 were followed up until stitch removal or discharge. Data was registered in a spreadsheet and processed statistically by statistical package for social sciences 10.0.
RESULTS
Overall incidence of surgical site infections was 2.2%, 0.5% in clean operation, 2.8% in clean contaminated, 9.1% in contaminated and 2.3% in dirty operations. Surgical site infections were found positively correlated with duration of operation (P=0.015) and number of stitches (P=0.017), but insignificantly associated with sex, age, type of operation and pre-operative hospitalization.
CONCLUSION
In conclusion, surgical site infections, with antibiotic use, were found low. Higher number of stitches and longer duration of operation were the risk factors.
目的
本研究旨在确定手术部位感染的发生率以及抗生素的使用情况。此外，将感染情况与手术类型、手术时长、缝线数量、术前住院时间、患者年龄及性别进行关联分析。
方法
对2000年8月1日至2000年11月30日期间在也门共和国萨那市科威特大学医院接受手术干预并进行术前抗生素预防的所有也门患者（N = 601）进行随访，直至拆线或出院。数据记录在电子表格中，并使用社会科学统计软件包10.0进行统计处理。
结果
手术部位感染的总体发生率为2.2%，清洁手术为0.5%，清洁-污染手术为2.8%，污染手术为9.1%，污秽手术为2.3%。发现手术部位感染与手术时长（P = 0.015）和缝线数量（P = 0.017）呈正相关，但与性别、年龄、手术类型及术前住院时间无显著关联。
结论
总之，使用抗生素的情况下手术部位感染发生率较低。缝线数量较多和手术时长较长是危险因素。
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