Bees M A, Andresén P, Mosekilde E, Givskov M
Department of Mathematics & Statistics, University of Surrey, GU2 7XH, UK.
Bull Math Biol. 2002 May;64(3):565-87. doi: 10.1006/bulm.2002.0287.
We report the first controlled measurements of expansion rates for swarming colonies of Serratia liquefaciens under different growth conditions, combined with qualitative observations of the organization of the colony into regions of differentiated cell types. Significantly, the results reveal that swarming colonies of S. liquefaciens can have an increasing expansion rate with time. We compare and contrast the expansion rate results with predictions from a recent mathematical model which coupled key hydrodynamical and biological mechanisms. Furthermore, we investigate whether the swarming colonies grow according to a power law or exponentially (for large times), as suggested by recent theoretical results.
我们报告了在不同生长条件下,对液化沙雷氏菌群体菌落扩张速率进行的首次对照测量,并结合了对菌落组织成不同细胞类型区域的定性观察。重要的是,结果显示液化沙雷氏菌的群体菌落扩张速率会随时间增加。我们将扩张速率结果与最近一个耦合关键流体动力学和生物学机制的数学模型的预测进行了比较和对比。此外,我们还研究了群体菌落是否如最近的理论结果所暗示的那样,按照幂律或指数规律(在较长时间内)生长。