[The role of disorders of "non-specific systems" of the brain in the pathogenesis of the Parkinsonian syndrome].

The authors conducted a clinico-physiological analysis of the syndrome of parkinsonism in different functional states (intense vigilance, flaccid vigilance, various phases and stages of night sleep, a hypnotic state) using the method of a polygraphic registration and an experimental-psychological study. The functional state of so-called nonspecific brain systems in parkinsonism and their disturbances in the pathogenesis of the disease was studied. A complicated character of shifts in different chains of the non-specific systems with various clinical forms and at different stages of the diseases were demonstrated. The authors proposed a method of quantitative evaluation of these shifts. It was demonstrated that motor, emotional-vegetative, somnic and electroencephalographic manifestations in parkinsonism correlated with the character and degree of the pathological changes in the non-specific, mainly activating brain systems.