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老年人股骨颈骨折:基于欧洲五维健康量表的功能结局与生活质量

Femoral neck fractures in the elderly: functional outcome and quality of life according to EuroQol.

作者信息

Tidermark Jan, Zethraeus Niklas, Svensson Olle, Törnkvist Hans, Ponzer Sari

机构信息

Department of Orthopaedics, Karolinska Institute at Stockholm Söder Hospital, Sweden.

出版信息

Qual Life Res. 2002 Aug;11(5):473-81. doi: 10.1023/a:1015632114068.

Abstract

The main purpose of this prospective study was to investigate the functional outcome and health-related quality of life according to EuroQol (EQ-5D) after a femoral neck fracture treated with internal fixation in relatively healthy elderly patients. We also aimed to validate the use of the EQ-5D in routine clinical follow-ups of this group of patients. The inclusion criteria were more than 65 years of age, absence of severe cognitive dysfunction, living independently, and unhindered walking ability preoperatively. The mean follow-up period was 17 months. The rated prefracture EQ-5Dindex scores showed good correspondence with the scores of an age-matched Swedish reference population. The EQ-5Dindex scores decreased from 0.78 before the fracture (based on recall) to 0.59 at 4 months and 0.51 at 17 months after surgery. The decrease was significantly larger among patients with fracture healing complications. There was a good correlation between the EQ-5Dindex scores and other outcome measures such as pain, mobility, independence in ADL and independent living status. The questionnaire response rate (EQ-5D) was 89-100% on different follow-up occasions. The EQ-5D appears to be an easy-to use instrument even for elderly patients with femoral neck fractures. Changes in the quality of life may be useful to identify patients who might benefit from reoperation, i.e. arthroplasty. The EQ-5D also appears to be a relevant clinical end-point in outcome studies.

摘要

这项前瞻性研究的主要目的是调查相对健康的老年患者股骨颈骨折内固定治疗后根据欧洲五维健康量表(EQ-5D)得出的功能结局和健康相关生活质量。我们还旨在验证EQ-5D在这类患者常规临床随访中的应用。纳入标准为年龄超过65岁、无严重认知功能障碍、术前独立生活且行走能力无障碍。平均随访期为17个月。骨折前EQ-5D指数评分与年龄匹配的瑞典参考人群评分显示出良好的对应关系。EQ-5D指数评分从骨折前(基于回忆)的0.78降至术后4个月的0.59和17个月的0.51。骨折愈合并发症患者的下降幅度明显更大。EQ-5D指数评分与疼痛、活动能力、日常生活活动独立性和独立生活状态等其他结局指标之间存在良好的相关性。在不同的随访时间点,问卷(EQ-5D)回复率为89%-100%。对于股骨颈骨折的老年患者,EQ-5D似乎是一种易于使用的工具。生活质量的变化可能有助于识别可能从再次手术(即关节置换术)中获益的患者。EQ-5D在结局研究中似乎也是一个相关的临床终点。

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