Güngür K, Bekir N A, Namiduru M
Department of Ophthalmology, Medical Faculty, Gaziantep University, Turkey.
Eur J Ophthalmol. 2002 May-Jun;12(3):232-7. doi: 10.1177/112067210201200311.
To report the ocular manifestations associated with brucellosis in an endemic area.
We prospectively evaluated 147 patients with the diagnosis of brucellosis between May 1996 to May 2000 and recorded the ocular and systemic findings. The diagnosis was based on clinical findings, positive serological and bacteriological tests (Brucella agglutination test: over 1/160 titer, blood culture).
Thirty-eight patients (26.0%) with brucellosis had ocular complications: conjunctivitis in 26 (17.7%), anterior uveitis in six (4.1%), posterior uveitis in one (0.7%), dacryoadenitis in two (1.4%), episcleritis in three (2.1%). Three of the seven patients with uveitis had spondylitis associated with brucellosis. Osteoarticular complications in brucellosis were more frequent in the patients with ocular involvement though the difference was not statistically significant compared with patients without ocular involvement.
Ocular manifestations are frequent in brucellosis so an ophthalmologic examination should be routinely performed in patients with brucellosis in endemic areas.
报告地方流行区布鲁氏菌病相关的眼部表现。
我们对1996年5月至2000年5月间确诊为布鲁氏菌病的147例患者进行前瞻性评估，并记录眼部和全身检查结果。诊断基于临床表现、血清学和细菌学检查阳性（布鲁氏菌凝集试验：滴度超过1/160，血培养）。
38例（26.0%）布鲁氏菌病患者出现眼部并发症：结膜炎26例（17.7%），前葡萄膜炎6例（4.1%），后葡萄膜炎1例（0.7%），泪腺炎2例（1.4%），巩膜炎3例（2.1%）。7例葡萄膜炎患者中有3例合并布鲁氏菌病相关脊柱炎。布鲁氏菌病患者中，眼部受累患者的骨关节并发症更为常见，尽管与未受累患者相比差异无统计学意义。
布鲁氏菌病患者眼部表现常见，因此地方流行区的布鲁氏菌病患者应常规进行眼科检查。
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