Increases in amino-cupric-silver staining of the supraoptic nucleus after sleep deprivation.
作者信息
Eiland Monica M, Ramanathan Lalini, Gulyani Seema, Gilliland Marcia, Bergmann Bernard M, Rechtschaffen Allan, Siegel Jerome M
机构信息
University of California, Los Angeles, CA, USA.
出版信息
Brain Res. 2002 Jul 26;945(1):1-8. doi: 10.1016/s0006-8993(02)02448-4.
Abstract
Sleep deprived rats undergo a predictable sequence of physiological changes, including changes in skin condition, increased energy expenditure, and altered thermoregulation. Amino-cupric-silver staining was used to identify sleep deprivation related changes in the brain. A significant increase in staining was observed in the supraoptic nucleus (SON) of the hypothalamus of rats with high sleep loss (>45 h) vs. their yoked controls. Follow-up experiments showed that staining was not significantly different in rats sleep deprived for less than 45 h, suggesting that injurious sleep deprivation-related processes occur above a threshold quantity of sleep loss. These anatomical changes suggest that the effects of sleep deprivation may be related to protein metabolism in certain brain regions.
摘要
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1
Cholinergic input to the supraoptic nucleus increases Fos expression and body temperature in rats.
Pflugers Arch. 2001 Jun;442(3):451-8. doi: 10.1007/s004240100557.
2
Opposite regulation of body temperature by cholinergic input to the paraventricular nucleus and supraoptic nucleus in rats.
Brain Res. 2001 Aug 3;909(1-2):102-11. doi: 10.1016/s0006-8993(01)02642-7.
3
Ionotropic histamine receptors and H2 receptors modulate supraoptic oxytocin neuronal excitability and dye coupling.
J Neurosci. 2001 May 1;21(9):2974-82. doi: 10.1523/JNEUROSCI.21-09-02974.2001.
4
Hypothalamic sleep-promoting mechanisms: coupling to thermoregulation.
Arch Ital Biol. 2001 Feb;139(1-2):63-75.
5
Neuronal Fos-like immunoreactivity in ouabain-induced hypertension.
Brain Res. 2000 Sep 8;876(1-2):17-21. doi: 10.1016/s0006-8993(00)02591-9.
6
7
Diurnal rhythms in neurohypophysial function.
Exp Physiol. 2000 Mar;85 Spec No:179S-186S. doi: 10.1111/j.1469-445x.2000.tb00022.x.
8
Differential progression of Dark Neuron and Fluoro-Jade labelling in the rat hippocampus following pilocarpine-induced status epilepticus.
Neuroscience. 2000;97(1):59-68. doi: 10.1016/s0306-4522(00)00026-9.
9
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Toxicol Pathol. 2000 Jan-Feb;28(1):70-83. doi: 10.1177/019262330002800109.
10
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Brain Res. 1999 Sep 4;840(1-2):184-93. doi: 10.1016/s0006-8993(99)01768-0.
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