两种新型阴道杀菌剂（聚苯乙烯磺酸盐和硫酸纤维素）可抑制阴道加德纳菌以及通常与细菌性阴道病相关的厌氧菌。
Two novel vaginal microbicides (polystyrene sulfonate and cellulose sulfate) inhibit Gardnerella vaginalis and anaerobes commonly associated with bacterial vaginosis.
作者信息
Simoes Jose A, Citron Diane M, Aroutcheva Alla, Anderson Robert A, Chany Calvin J, Waller Donald P, Faro Sebastian, Zaneveld Lourens J D
机构信息
Department of Obstetrics and Gynecology, Rush University, Rush-Presbyterian-St Luke's Medical Center, 1653 W Congress Parkway, Chicago, IL 60612, USA.
出版信息
Antimicrob Agents Chemother. 2002 Aug;46(8):2692-5. doi: 10.1128/AAC.46.8.2692-2695.2002.
Abstract
This is the first report demonstrating the in vitro inhibitory activity of two novel microbicides (cellulose sulfate and polystyrene sulfonate) against bacterial vaginosis (BV)-associated bacteria. Vaginal application of these microbicides not only may reduce the risk of acquisition of human immunodeficiency virus and other sexually transmitted infection-causing organisms but may also decrease the incidence of BV.
摘要
这是首份证明两种新型杀菌剂（硫酸纤维素和聚苯乙烯磺酸盐）对细菌性阴道病（BV）相关细菌具有体外抑制活性的报告。阴道应用这些杀菌剂不仅可能降低感染人类免疫缺陷病毒及其他性传播感染病原体的风险，还可能降低BV的发病率。
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