猫对实验性刚地弓形虫感染的血清学反应。（注：原文中病原体名称有误，应为“刚地弓形虫”，而不是“犬新孢子虫”，这里按照正确内容翻译）

Serologic responses of cats against experimental Sarcocystis neurona infections.

作者信息

Dubey J P, Lindsay D S, Saville W J A

机构信息

United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Parasite Biology, Epidemiology and Systematics Laboratory, Building 1001, Beltsville, MD 20705-2350, USA.

出版信息

Vet Parasitol. 2002 Aug 2;107(3):265-9. doi: 10.1016/s0304-4017(02)00157-7.

DOI:10.1016/s0304-4017(02)00157-7

PMID:12127255

Abstract

Sarcocystis neurona is the most important cause of a neurologic disease of horses, equine protozoal myeloencephalitis (EPM). Cats and other carnivores can act as its intermediate hosts and horses are aberrant hosts. Little is known of the sero-epidemiology of S. neurona infections in cats. In the present study, antibodies to S. neurona were evaluated by the S. neurona agglutination test (SAT). Cats fed sporocysts from the feces of naturally infected opossums or inoculated intramuscularly with S. neurona merozoites developed high levels (> or =1:4000) of SAT antibodies. Antibodies to S. neurona were not found in a cat inoculated with merozoites of the closely related parasite, Sarcocystis falcatula. These results should be useful in studying sero-epidemiology of S. neurona infections in cats.

摘要

肉孢子虫是马匹神经疾病——马属动物原虫性脑脊髓炎（EPM）的最重要病因。猫和其他食肉动物可作为其中间宿主，而马是异常宿主。关于猫体内肉孢子虫感染的血清流行病学知之甚少。在本研究中，通过肉孢子虫凝集试验（SAT）评估了针对肉孢子虫的抗体。喂食来自自然感染负鼠粪便中的孢子囊或经肌肉接种肉孢子虫裂殖子的猫，产生了高水平（≥1:4000）的SAT抗体。在用密切相关的寄生虫——镰刀肉孢子虫的裂殖子接种的猫中未发现针对肉孢子虫的抗体。这些结果对于研究猫体内肉孢子虫感染的血清流行病学应具有一定作用。