Hall Alan H, Blomet Joel, Mathieu Laurence
Department of Emergency Medicine, Texas Tech University Health Sciences Center-El Paso, 79936, USA.
Vet Hum Toxicol. 2002 Aug;44(4):228-31.
Eye/skin chemical splashes are a significant problem. Diphoterine is an hypertonic, polyvalent, amphoteric compound developed in France as an eye/skin chemical splash water-based decontamination solution. In vitro and in vivo, it actively decontaminates approximately 600 chemicals, including acids, alkalis, oxidizing and reducing agents, irritants, lacrimators, solvents, alkylating agents, and radionuclides. Its chemical bond energy for such agents is greater than that of tissue receptors. Its hypertonicity impedes chemical tissue penetration and may remove some amount of skin/cornea-absorbed toxicants not already bound to tissue receptors. Diphoterine chemical reactions are not exothermic. Diphoterine and its acid/alkali decontamination residues are not irritating to the eyes or skin; it is essentially nontoxic. Diphoterine can prevent eye/skin burns following chemical splashes and results in nearly immediate pain relief.
眼部/皮肤化学物质飞溅是一个重大问题。迪弗碱（Diphoterine）是一种高渗、多价、两性化合物，在法国研发，用作眼部/皮肤化学物质飞溅的水基去污溶液。在体外和体内，它能有效净化约600种化学物质，包括酸、碱、氧化剂、还原剂、刺激物、催泪剂、溶剂、烷基化剂和放射性核素。它与这些物质的化学键能大于组织受体的化学键能。其高渗性阻碍化学物质穿透组织，并可去除一些尚未与组织受体结合的皮肤/角膜吸收的毒物。迪弗碱的化学反应不是放热反应。迪弗碱及其酸碱去污残留物对眼睛或皮肤无刺激性；它基本无毒。迪弗碱可预防化学物质飞溅后导致的眼部/皮肤灼伤，并能几乎立即缓解疼痛。
