ε-氨基己酸与肾脏并发症：病例报告及文献综述

Epsilon-aminocaproic acid and renal complications: case report and review of the literature.

作者信息

Manjunath G, Fozailoff A, Mitcheson D, Sarnak M J

机构信息

Department of Medicine, New England Medical Center, Boston, MA 02111, USA.

出版信息

Clin Nephrol. 2002 Jul;58(1):63-7. doi: 10.5414/cnp58063.

DOI:10.5414/cnp58063

PMID:12141409

Abstract

Epsilon-aminocaproic acid (EACA) is a potent anti-fibrinolytic agent that is used in the treatment of excessive bleeding resulting from a systemic fibrinolytic state. It can also be used to treat hematuria through its action on decreasing urinary fibrinolysis. A broad range of renal complications has been ascribed to EACA. Although they are rare, they may be life-threatening and should therefore be immediately recognized.

摘要

ε-氨基己酸（EACA）是一种强效抗纤维蛋白溶解剂，用于治疗全身性纤维蛋白溶解状态导致的出血过多。它还可通过减少尿液纤维蛋白溶解作用来治疗血尿。EACA已被归因于多种肾脏并发症。虽然它们很少见，但可能危及生命，因此应立即识别。