Allmers Henning, Schmengler Jörg, Skudlik Christoph
Department of Dermatology, Environmental Medicine and Health Sciences, University of Osnabrück, Sedanstrasse 115, 49090 Osnabrück, Germany.
J Allergy Clin Immunol. 2002 Aug;110(2):318-23. doi: 10.1067/mai.2002.126461.
The development of occupational asthma and allergic skin reactions caused by natural rubber latex (NRL) allergy are risks for health care workers. There are few published studies to suggest that intervention programs to reduce exposure will lead to primary prevention of sensitization.
This study assesses the effects of intervention to reduce the incidence of NRL allergy in personnel working in health care facilities insured by the German statutory accident insurance company for health care workers, Berufsgenossenschaft für Gesundheitsdienst und Wohlfahrtspflege, with approximately 3 million insured employees, by switching to powder-free NRL gloves.
The timing of introduction of intervention strategies, such as education of both physicians and administrators, together with regulations demanding that health care facilities only purchase low-protein, powder-free NRL gloves are reported. We reviewed the annual numbers of reported suspected cases of NRL-caused occupational allergies and the amount and type of gloves used in German acute-care hospitals since 1986.
The purchase of powder-free NRL examination gloves exceeded that of powdered gloves for the first time in 1998. This only became true for powder-free NRL sterile gloves 2 years later in 2000. The incidence of suspected occupational NRL allergy cases rose until 1998 and has declined steadily since. There was a 2-year lag between the beginning of the decline in the purchase of powdered NRL examination gloves and the beginning of a decline in suspected NRL-caused occupational asthma cases.
Despite the effect of increased recognition of NRL allergies, education about NRL allergies in health care facilities combined with the introduction of powder-free gloves with reduced protein levels has been associated with a decline in the number of suspected cases of occupational allergies caused by NRL in Germany on a nationwide scale. These results clearly indicate that primary prevention of occupational NRL allergies can be achieved if these straightforward and practical interventions are properly carried out and maintained.
天然橡胶乳胶(NRL)过敏引发的职业性哮喘和过敏性皮肤反应对医护人员的健康构成风险。鲜有已发表的研究表明,旨在减少接触的干预项目能够实现致敏的一级预防。
本研究评估了干预措施对德国医护人员法定事故保险公司(职业卫生与福利协会,约有300万参保员工)所承保的医疗机构工作人员中NRL过敏发生率的影响,干预措施是改用无粉NRL手套。
报告了干预策略的引入时间,如对医生和管理人员的培训,以及要求医疗机构仅购买低蛋白、无粉NRL手套的规定。我们回顾了自1986年以来德国急症护理医院上报的疑似NRL所致职业过敏病例的年度数量以及所用手套的数量和类型。
1998年,无粉NRL检查手套的采购量首次超过了有粉手套。两年后的2000年,无粉NRL无菌手套的采购量才首次超过有粉手套。疑似职业性NRL过敏病例的发生率在1998年之前一直上升,此后则稳步下降。有粉NRL检查手套采购量下降的开始时间与疑似NRL所致职业性哮喘病例下降的开始时间之间存在两年的滞后。
尽管对NRL过敏的认知有所提高,但德国医疗机构中关于NRL过敏的教育,以及引入蛋白含量降低的无粉手套,在全国范围内与NRL所致职业过敏疑似病例数量的下降相关。这些结果清楚地表明,如果正确实施并维持这些直接且实用的干预措施,就能够实现职业性NRL过敏的一级预防。