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朱拉隆功国王纪念医院结直肠癌患者的回顾性研究。

A retrospective study of colorectal cancer patients in King Chulalongkorn Memorial Hospital.

作者信息

Kullavanijaya Pinit, Rerknimitr Rungsun, Amornrattanakosol Jaturong

机构信息

Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 2002 Jun;85 Suppl 1:S85-90.

Abstract

To determine the basic clinical information of colorectal cancer in Thailand, the authors retrospectively reviewed the medical records and pathological reports of 293 patients with histologically proven colonic cancer but only 137 patients met the inclusion criteria in King Chulalongkorn Memorial Hospital during the three-year period from July 1997 to June 2000. There were 72 males (53%) and 65 females (47%) with an age ranging from 24 to 90 years (mean age 61.2 years). Among these, 115 patients (83.9%) were older than 50 years. Bowel-habit change, weight loss and mucous bloody diarrhea were the most common presentations respectively. Distal colorectal cancer is the most common site of colonic cancer (71.3%) and 28.7 per cent were at the proximal colon. Dukes' D (35%) was the most common colorectal cancer staging in the hospital. Considering the sites of metastases, liver was the most common site of metastases (61%). The most common cell type was moderately-differentiated adenocarcinoma. Low anterior resection was the most common surgical procedure (24.9%) since the tumor was usually located distally. In conclusion, 1) bowel habit change was the most common presentation for colorectal cancer at the hospital and the majority of patients were elderly. 2) Colorectal cancer was usually found at the late stage which was associated with poor prognosis.

摘要

为确定泰国结直肠癌的基本临床信息,作者回顾性分析了293例经组织学证实为结肠癌患者的病历和病理报告,但在1997年7月至2000年6月的三年期间,朱拉隆功国王纪念医院仅有137例患者符合纳入标准。其中男性72例(53%),女性65例(47%),年龄范围为24至90岁(平均年龄61.2岁)。其中,115例患者(83.9%)年龄超过50岁。排便习惯改变、体重减轻和黏液血便分别是最常见的症状。结直肠癌最常见的部位是远端结肠(71.3%),28.7%位于近端结肠。Dukes' D期(35%)是该医院最常见的结直肠癌分期。考虑转移部位,肝脏是最常见的转移部位(61%)。最常见的细胞类型是中分化腺癌。低位前切除术是最常见的手术方式(24.9%),因为肿瘤通常位于远端。总之,1)排便习惯改变是该医院结直肠癌最常见的症状,且大多数患者为老年人。2)结直肠癌通常在晚期发现,预后较差。

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