脊髓损伤患者的马乔林溃疡
Marjolin's ulcer in patients with spinal cord injury.
作者信息
Eltorai Ibrahim M, Montroy Robert E, Kobayashi Mark, Jakowatz James, Guttierez Paul
机构信息
Spinal Cord Injury Center, VA Medical Center, Irvine, California, USA.
出版信息
J Spinal Cord Med. 2002 Fall;25(3):191-6. doi: 10.1080/10790268.2002.11753621.
BACKGROUND
The term "Marjolin's ulcer" is now synonymous with malignant transformation, usually ectodermal and rarely mesenchymal, of chronic ulcers, sinus tracts, and burn scars.
DESIGN
Literature search and personal experience with 5 patients during a 30-year period in a spinal cord injury center.
FINDINGS
Five cases of Marjolin's ulcer diagnosed among approximately 10,000 patients indicate the rarity of the metaplasia. All cases were fatal.
CONCLUSIONS
Chronic pressure ulcers of more than 10 years' duration should be biopsied to rule out malignancy, especially with any change in the nature of the ulcer (eg, exuberant granulation and/or bleeding).
背景
“马乔林溃疡”一词现指慢性溃疡、窦道和烧伤瘢痕发生的恶性转化，通常为外胚层来源，间充质来源罕见。
设计
文献检索及在一家脊髓损伤中心30年间对5例患者的个人经验。
结果
在约10000例患者中诊断出5例马乔林溃疡，表明这种化生很罕见。所有病例均死亡。
结论
病程超过10年的慢性压疮应进行活检以排除恶性肿瘤，尤其是溃疡性质有任何改变（如肉芽组织过度增生和/或出血）时。
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