Busch Betsy, Biederman Joseph, Cohen Louise Glassner, Sayer Julie M, Monuteaux Michael C, Mick Eric, Zallen Barry, Faraone Stephen V
Department of Pediatrics, Tufts University School of Medicine in Boston, USA.
Psychiatr Serv. 2002 Sep;53(9):1103-11. doi: 10.1176/appi.ps.53.9.1103.
Conventional wisdom among pediatricians has been that children with attention-deficit hyperactivity disorder (ADHD) who receive their diagnosis and are managed in the primary care setting have fewer comorbid psychiatric disorders and milder impairments than those seen in psychiatric clinics. The authors sought to determine whether comorbidity and clinical correlates of ADHD differ among children in these two settings.
A case-control study design was used. Participants were 522 children and adolescents of both sexes, six to 18 years of age, with (N=280) and without (N=242) ADHD. Participants were drawn from pediatric and psychiatric clinics in a tertiary care hospital and a health maintenance organization in a large metropolitan area. Assessments were conducted with standardized measures of psychiatric, cognitive, social, academic, and family function.
The number, type, clusters, and age at onset of ADHD symptoms were nearly identical for youths at pediatric and psychiatric ascertainment sources. Regardless of source, participants with ADHD were significantly more likely than controls to have a higher prevalence of mood disorders, other disruptive behavior, anxiety disorders, and substance use disorders. Significant impairments of intellectual, academic, interpersonal, and family functioning did not differ between ascertainment sources.
Children with ADHD from both psychiatric and pediatric practices have prototypical symptoms of the disorder; high levels of comorbidity with mood, anxiety, and disruptive behavior disorders; and impairments in cognitive, interpersonal, and academic function that do not differ by ascertainment source. These findings suggest that children cared for in pediatric practice have similar levels of comorbidity and dysfunction as psychiatrically referred youth.
儿科医生的传统观念认为,在初级保健机构接受诊断和治疗的注意力缺陷多动障碍(ADHD)儿童,其共病的精神障碍较少,功能损害也比在精神科诊所就诊的儿童轻。作者试图确定这两种环境下ADHD儿童的共病情况及临床相关因素是否存在差异。
采用病例对照研究设计。参与者为522名6至18岁的儿童和青少年,其中280名患有ADHD,242名未患ADHD。参与者来自一家三级护理医院的儿科和精神科诊所,以及一个大城市地区的健康维护组织。使用标准化的精神、认知、社会、学业和家庭功能测量方法进行评估。
在儿科和精神科确诊来源的青少年中,ADHD症状的数量、类型、聚类和发病年龄几乎相同。无论确诊来源如何,患有ADHD的参与者比对照组更有可能出现更高比例的情绪障碍、其他破坏性行为、焦虑障碍和物质使用障碍。在确诊来源之间,智力、学业、人际和家庭功能的显著损害并无差异。
来自精神科和儿科的ADHD儿童都有该疾病的典型症状;与情绪、焦虑和破坏性行为障碍的共病率很高;认知、人际和学业功能的损害在确诊来源上没有差异。这些发现表明,在儿科接受治疗的儿童与转介到精神科的儿童共病和功能障碍水平相似。