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硬质支气管镜检查及支架置入术治疗食管癌致气道梗阻

Rigid bronchoscopy and stenting for esophageal cancer causing airway obstruction.

作者信息

Chan Kenneth Ping Wah, Eng Philip, Hsu Anne A L, Huat Goh Meng, Chow Mark

机构信息

Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.

出版信息

Chest. 2002 Sep;122(3):1069-72. doi: 10.1378/chest.122.3.1069.

Abstract

BACKGROUND

Thirty percent of patients with esophageal cancer have malignant involvement of the major airways, leading to respiratory distress and life-threatening major airway obstruction. Tracheobronchial stenting has been reported to be effective in providing sustained relief from obstruction.

METHODS

We conducted a chart review of all patients with advanced inoperable esophageal cancer who had malignant tracheobronchial obstruction requiring rigid bronchoscopy and airway stenting at our institution between June 1998 and July 2001. Outcome measures, which included survival, efficacy, and complications, were recorded.

RESULTS

There were 11 patients (4 women) with a mean age of 61 years. Five patients had distant metastases at the time they underwent rigid bronchoscopy. Four patients who required mechanical ventilation for respiratory failure were successfully weaned off mechanical ventilation after the stenting procedure. All patients with dyspnea had immediate relief of respiratory symptoms, which was sustained for seven patients (64%). The mean duration of survival was 61 days. Two patients required repeat procedures, one for stent dislodgment on extubation and the other for stent migration.

CONCLUSION

Stenting in patients with malignant tracheobronchial obstructions due to advanced esophageal cancer achieves immediate, dramatic, and sustainable relief in respiratory symptoms, conferring a survival benefit in patients whose conditions are otherwise deemed to be terminal.

摘要

背景

30%的食管癌患者存在主要气道的恶性侵犯,导致呼吸窘迫和危及生命的主要气道梗阻。据报道,气管支气管支架置入术能有效缓解梗阻。

方法

我们对1998年6月至2001年7月期间在我院因恶性气管支气管梗阻需要硬支气管镜检查和气道支架置入的所有晚期不可手术食管癌患者进行了病历回顾。记录了包括生存、疗效和并发症在内的结果指标。

结果

共有11例患者(4例女性),平均年龄61岁。5例患者在接受硬支气管镜检查时已有远处转移。4例因呼吸衰竭需要机械通气的患者在支架置入术后成功脱机。所有呼吸困难患者的呼吸道症状均立即缓解,7例患者(64%)症状持续缓解。平均生存时间为61天。2例患者需要重复手术,1例因拔管时支架移位,另1例因支架迁移。

结论

对于因晚期食管癌导致恶性气管支气管梗阻的患者,支架置入术能立即、显著且持续地缓解呼吸道症状,为病情本被视为终末期的患者带来生存益处。

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