人类疱疹病毒8型基因编码一种功能性胸苷酸合成酶。
Human herpesvirus 8 gene encodes a functional thymidylate synthase.
作者信息
Gáspár Gábor, De Clercq Erik, Neyts Johan
机构信息
Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium.
出版信息
J Virol. 2002 Oct;76(20):10530-2. doi: 10.1128/jvi.76.20.10530-10532.2002.
Abstract
We demonstrate that human herpesvirus 8, obtained from the lymphoma cell line BC-3 as well as from Kaposi's sarcoma lesions, carries a gene that encodes a functional thymidylate synthase (TS). The particular characteristics of this enzyme are studied and compared to the characteristics of TSs encoded by other organisms.
摘要
我们证明，从淋巴瘤细胞系BC-3以及卡波西肉瘤病变中获得的人类疱疹病毒8携带一个编码功能性胸苷酸合成酶（TS）的基因。对该酶的特殊特性进行了研究，并与其他生物体编码的TS的特性进行了比较。
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